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Microphysiological System Solutions

Enhance the relevance of your research

Drug discovery endeavors require a deep understanding of biological systems and their response to potential therapeutics. That’s where microphysiological systems (MPS) play a pivotal role. They offer a more accurate representation of cellular biology that goes beyond traditional approaches, enabling researchers to understand disease mechanisms and find new treatments that translate into clinical response.

If you are working on your next 3D cell model project, and trying to select the right culture method, genetically modify your cells, automate your workflow, or analyze your samples and data, at Revvity we have microphysiological system solutions to partner with you with the purpose of reaching your goals. Together, we can redefine what’s possible by developing innovative treatments and precise therapeutic solutions to improve human health and lives around the world.
 

Animal modelsStem cell and iPSC-derived disease modelsOrgan-on-chipBioprinted modelsSpheroids and organoids
Physiological model solutions benefits interactive imageThis SVG depicts various shapes and models related to spheroids and organoids in biological studies, including representations of animal models and stem cell-derived disease models.Animal modelsStem cell and iPSC-derived disease modelsOrgan-on-chipBioprinted modelsSpheroids and organoids


For research use only. Not for use in diagnostic procedures.

Microphysiological System Solutions
Culture

When it comes to developing advanced physiological models — it’s critical to select the cell model with the right genomic context and biological function to recapitulate a healthy or diseased phenotype.

Achieving this level of accuracy requires tightly controlled culture conditions and reliable cell counting for cell seeding. Choosing a 2D or 3D cell culture method depends on the biological question, complexity of the desired model, and readout technology. Cells can be grown as monolayers, single spheroids in ultra-low attachment (ULA) plates, or cultured in hydrogels, offering a variety of options to enhance your research capabilities. Count on us to expertly scale up these methods, utilizing liquid handling techniques.

Featured products:
growdex hydrogels
GrowDex Hydrogels
We offer a range of products for scalable animal-free 3D cell culture applications, providing convenience and consistent results.
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マイクロプレート
適切なマイクロプレートを選択することは、アッセイにおいて非常に重要ですが、見落とされがちです。正しいマイクロプレートは貴重なデータを提供するのに役立ちますが、間違ったマイクロプレートはデータの欠落や不正確さを招き、プロジェクトのタイムラインや最終的なコストの上昇につながります。
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Fontus Liquid Handling Workstation-Revvity-512x288
Fontus Workstations
With easy-to-use software, optimized deck access, verified protocols, and reformatting capabilities to simplify your workflows and improve turnaround times
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Cell Counting & Image Cytometry Instruments
Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability, immunophenotyping, and perform a range of other routine cell-based assays.
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Viral Vector Products
Viral vectors are the most efficient vehicles for gene delivery into a specific cell type or tissue for a wide array of research purposes.
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Recombinant Proteins
Our portfolio includes over 2,000 bioactive human, mouse, and rat recombinant proteins developed in-house.
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crispr technologies
CRISPR Technologies
CRISPR-Cas9 genome engineering technologies hold great promise for understanding diseases and for the development of life saving treatments.
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Treatment

In modern drug discovery, multiple screening methods play a vital role in identifying potential drug targets and eventual drug candidates. Traditionally, small molecule libraries were screened for compounds acting on a known molecule or for a desired biological effect. However, a drug candidate is only as good as its target.

To ensure the utmost precision, today’s drug discovery leverages gene editing or gene silencing methods such as CRISPR or siRNAs to identify suitable drug targets. Understanding the causal gene behind a phenotype or genes that contribute to a phenotype can significantly boost the confidence in a new drug candidate. Get ready to experience advancements in your research as we deliver convenience and efficiency.

Featured products:
Fontus Liquid Handling Workstation-Revvity-512x288
Fontus Workstations
With easy-to-use software, optimized deck access, verified protocols, and reformatting capabilities to simplify your workflows and improve turnaround times
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crispr technologies
CRISPR Technologies
CRISPR-Cas9 genome engineering technologies hold great promise for understanding diseases and for the development of life saving treatments.
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rna interference
RNA Interference
Dharmacon™ siRNA, shRNA, and microRNA-based reagents, leading the field for nearly 30 years providing highly specific and efficient gene silencing.
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Model Analysis

Selecting the right method for measuring the biological response of 3D cell models depends on the specific research question and the characteristics of the model system in use.

Whether you’re repeatedly monitoring microtissue size or measuring sensitive detection of secreted proteins, each readout type poses unique challenges that can be overcome with the right tools. Our microplate readers, high-content analysis systems, and innovative reagents are complemented by specially designed microplates. Together, they shine a light on your samples, offering powerful insights to propel your research forward.

Featured products:
LabChip GX Touch Nucleic Acid Analyzer
LabChip GX タッチ核酸アナライザー
DNA、RNA、NGSライブラリーーの正確なサイズ決定、定量、品質管理。 LabChip® GX Touch™核酸アナライザーは、ゲノムのサイジングと定量を行うための包括的なソリューションです。以下の機能を備えています: <ul> <li> アガロースゲルよりも数時間速いDNAおよびRNAサンプルの完全性の定量 </li> <li> cfDNA、PCRフリーライブラリーー、ChIP-seqライブラリーーのような希少または低濃度サンプルの最大化 </li> <li> DNAスミアでは25 pg/µL、フラグメントでは0.5 pg/µLまで正確に定量可能 </li> <li> NGSライブラリーー前処理分析およびQC </li> <li> フレキシブルなスループットオプションにより、コスト効率に優れています - 96ウェルまたは384ウェル(HT)フォーマット </li> <li> データ可視化オプション(エレクトロフェログラム、バーチャルゲル、表形式レポート) </li> </ul> LabChip GX Touch核酸アナライザは、DNAおよびRNAの様々な分析にも対応しており、最小限のインプットで比類のないゲノムデータ品質を提供します。低濃度で貴重なサンプルの場合、LabChip® DNA High SensとRNA Picoアッセイは、信頼性の高い測定とサンプル保存のための理想的な選択です。LabChip GX Touch核酸アナライザは、約30秒でゲノムを完全に分析し、核酸定量ワークフローのボトルネックを解消します。高分解能分析により、2 pg/µLのサンプルから5 bpまでのDNA断片や塗抹標本の正確なサイズ決定と定量が可能です。 このシステムは、最小限の入力要件で比類のないゲノムデータ品質を提供するNGS 3Kアッセイを含む、幅広いDNA分析オプションを提供します。この高い感度は、濃度が低く、サンプルが貴重で、その保存が不可欠なgDNAやPCRフリーのDNA定量に理想的な装置にもなっています。 mRNAベースのワクチンの純度および完全性解析 メルクの研究者は、LabChip® RNA アッセイを使用して、mRNA ワクチンの純度と完全性を評価するアッセイ法を開発しました。この迅速で簡便かつ効率的なワークフローは、ワクチン開発のスピードアップと、製造量の増加による需要の増加に対応するのに役立ちました。 このシステムは、NGS 3KアッセイやcfDNAアッセイを含む幅広いDNA分析オプションを提供し、最小限の入力要件で比類のないゲノムデータ品質を実現します。この高い感度は、濃度が低く、サンプルが貴重で、その保存が不可欠なgDNA、cfDNA、PCRフリーのDNA定量に理想的な装置にもなっています。 外形寸法 <ul> <li> 高さ69cm </li> <li> 幅 51 cm </li> <li> 奥行き 49 cm</li> </ul> <ul> </ul>
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3D Cell Model Imaging and Analysis
3D cell culture models, such as spheroids, organoids, and microtissues, have gained popularity as tools for research, drug discovery and toxicity studies.
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microplate readers
マイクロプレートリーダー
Revvityのプレートリーダー製品群は、今日のラボの多様なアッセイ要件に対応する最新の検出技術を備えています。
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immunoassays
Immunoassays

Since their introduction in the 1950’s, immunoassays have been an integral part of research and drug discovery.

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Luminescence Assays
Luciferase assays allow for the study of transcriptional gene expression, virus life cycles, and cell viability.
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nucleic acid isolation
核酸分離
Revvityは、25年以上にわたって確立されたchemagic技術に基づき、ユニークで効率的な核酸分離法を提供しています。
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Cell Counting & Image Cytometry Instruments
Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability, immunophenotyping, and perform a range of other routine cell-based assays.
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Multiomics and TotalSeq Reagents by BioLegend
Multiomics provides unparalleled protein and genetic analysis. Explore how our TotalSeq™ reagents can be integrated into your existing workflows and expand your capabilities.
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Data Analysis

Extracting insights from complex 3D datasets is no easy task. It requires the meticulous analysis of readouts and vast amounts of information (in context). But no worries—we’ve got you covered.

With our scientific software and informatics solutions, you gain the ultimate tools to optimize 3D cell model imaging. Seamlessly aggregate, search, mine, and visualize critical data, converting it into actionable insights that drive your research forward. We are here to help you meet the challenges of data analysis head on—so you can embark on a journey of ground-breaking discoveries.

Featured products:
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Signals Image Artist

Signals Image Artist has powerful capabilities for processing, analyzing, storing, and sharing all your high-content screening and cell imaging data – so you can significantly cut your time to results.

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signals Research Suite
Signals Research Suite

Make your innovations a reality with the first unified, cloud-native SaaS R&D platform that streamlines scientific complexity and promotes collaboration.

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Services

Discover how our complex cell model screening services can accelerate your drug discovery and development goals. Our team leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells to provide more biologically relevant data. This allows for better prediction of human responses to therapeutic interventions in immuno-oncology.

From assay design to high-throughput screening, we provide an end-to-end service that supports every phase of your drug development, with dedicated project management you can trust.

Featured services:
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Advanced 3D cell culture models services

Our complex cell model screening services leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells, providing more biologically relevant data.

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