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A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.

HCS Publication List
A selection of publications from 2022 and 2023 using Revvity HCS systems are featured here.

HCS featured publications for infectious disease
This provides a list of various HCS publications in the area of infectious disease (viral, parasitic, and bacterial).

High content screening in three dimensions
This paper provides a recommended workflow for 3D HCS analysis, with a focus on reducing the 3D image analysis time by utilizing High Performance Computing.

Phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes
Application note describing phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes using the Opera Phenix high-content screening system

Opera Phenix Plus High-Content Screening System Brochure
Opera Phenix ® Plus high-content screening system designed for fast response analysis for sensitive confocal imaging.

How to perform successful long term live cell imaging in a high-content analysis system
How to perform successful long term live cell imaging in a high-content analysis system

Bone morphogenetic protein 8B - a promising therapeutic avenue for NASH treatment
Bone Morphogenetic Protein 8B investigated as a Promising Therapeutic Avenue for NASH Treatment

Phenotypic characterization of mitochondria in breast cancer cells using morphology and texture properties
This case study validates the use of STAR morphology and SER texture features to quantifiably characterize mitochondrial morphology and to detect changes induced by drug treatments.

Measuring FRET using the Opera™ Phenix™ high-content screening system
Here, we present a FRET-based high-content screening assay to study the interaction of the anti-apoptotic protein Bcl-XL with the pro-apoptotic protein Bad.

Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.

PhenoVue Cell Painting Kit 1 x 384-Well Plate Product Information Sheet
Product Information Sheet for PhenoVue Cell Painting Kit 1 x 384-Well Plate


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