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Solutions for precision medicine research
Our wide range of technologies can help you gain the knowledge you need to identify genomic vulnerabilities, screen functional responses, and evaluate how well a treatment is working.
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Solutions for infectious disease research and discovery
Our diverse infectious disease research portfolio helps researchers make critical discoveries through genomic, protein, cell, and in vivo analysis.
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Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
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