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Whitepaper
Gene editing of primary immune cells to aid next-generation cellular immunotherapies
Researchers have successfully deployed CRISPRa/i in primary human T cells, offering critical insights into the pathways required for cytokine regulation.
Brochure
CRISPR workflow solutions brochure
This brochure details the different CRISPR screening methods, including pooled and arrayed screens, and highlights various CRISPR applications such as disease modeling, pathway analysis, target identification, and cell and gene therapy.
Brochure
Decoding library complexity
This document provides guidance on the applications in which NEXTFLEX UDI-UMI Barcodes can be used.
Application Note
TotalSeq™ and DepleteX® technologies for efficient analysis of the cellular transcriptome
Read this app note to explore the compatibility of TotalSeq™ and DepleteX® kits in 10x Genomics workflows for efficient analysis of the cellular transcriptome.
Guide
Single Cell Sequencing with DepleteX® Getting Started
This document provides guidance to ensure customer success on their first single cell experiment using DepleteX® technology
Guide
Quick Guide to Cell Ranger
This document describes how to run Cell Ranger to observe the benefits of DepleteX® Single Cell RNA Boost kit on single-cell sequencing.
Application Note
Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
Infographic
Functional genomic screening in drug discovery
In this infographic we present two screening approaches, pooled and array, summarize advantages, read-out methods and available products and technologies.
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