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Whitepaper
Applying functional genomics strategies to high-content phenotypic screening
Explore cutting-edge functional genomics and high-content phenotypic screening in drug discovery. Download our whitepaper to learn about innovative techniques, best practices, and strategies for leveraging high-content imaging methods like cell painting to advance your research. Unlock the potential of genomic profiling and morphological analysis for therapeutic interventions
Brochure
Pooled functional genomic screening solutions and services
Functional genomic screening has the potential to reshape drug discovery, enhance our understanding of biological systems, and revolutionize personalized medicine.
Application Note
Evaluation of cell free fetal DNA cffDNA extraction on the chemagic 360 instrument with the FetoGnost Kit RhD to determine fetal RhD status
Explore automated cffDNA extraction for fetal RhD genotyping. Combine chemagic 360 technology with FetoGnost Kit RHD for efficient, non-invasive prenatal testing.
Application Note
Automated microRNA purification with chemagic 360 instrument
Discover efficient microRNA purification using the chemagic 360 instrument. This application note shows the workflow for miRNA isolation, improving throughput and reliability in molecular biology research.
Application Note
Best practices to measure cytokines in whole blood with AlphaLISA
Streamline your cytokine detection with no-wash assays, while overcoming the typical challenges associated with whole blood samples.
Brochure
Pooled functional genomic screening brochure
Functional genomic screening has the potential to reshape drug discovery, enhance our understanding of biological systems, and revolutionize personalized medicine.
Brochure
CRISPR workflow solutions brochure
This brochure details the different CRISPR screening methods, including pooled and arrayed screens, and highlights various CRISPR applications such as disease modeling, pathway analysis, target identification, and cell and gene therapy.
Application Note
Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
Infographic
Functional genomic screening in drug discovery
In this infographic we present two screening approaches, pooled and array, summarize advantages, read-out methods and available products and technologies.
Technical Note
A scalable and reproducible workflow for high-content analysis of cytotoxic effects in RASTRUM 3D cell cultures
Explore our Technical Note on a scalable workflow for high-content cytotoxicity analysis in 3D cell cultures. Discover reproducible 3D model creation, tailored microenvironment techniques, and enhanced imaging methods for accurate drug testing.
Whitepaper
Gene editing of primary immune cells to aid next-generation cellular immunotherapies
Researchers have successfully deployed CRISPRa/i in primary human T cells, offering critical insights into the pathways required for cytokine regulation.
Technical Note
PROTAC degraders targeting CDK4/CDK6 for the study of cell cycle regulation in oncology
Explore the cell cycle with AlphaLISA™ SureFire® Ultra™ and investigate Cyclin D1 and key proteins' roles in cancer prognosis, PROTAC, and NRG1 treatments.
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