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Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.

Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models

Brightfield and Fluorescent Image Analysis for Screening Applications using the Celigo Adherent Cell Cytometer
Brightfield and Fluorescent Image Analysis for Screening Applications using the Celigo Adherent Cell Cytometer

Cell-mediated cytotoxicity assay by high-throughput direct cell counting in microplates using fluorescence-based image cytometry
Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry

A high-throughput image cytometry-based screening method for the detection of IL2-induced peripheral blood mononuclear cell-mediated cytotoxicity
A high-throughput image cytometry-based screening method for the detection of IL2-induced peripheral blood mononuclear cell-mediated cytotoxicity

Real-time Caspase 3/7 measurement of suspension and adherent cells using the Celigo image cytometer
Real-time Caspase 3/7 measurement of suspension and adherent cells using the Celigo image cytometer

Validating and optimizing single cell sorting of FACS using Celigo image cytometry
Validating and optimizing single cell sorting of FACS using Celigo image cytometry

How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.

Illuminating the path to innovation: Revvity's high content screening services
This scientific poster presented at ELRIG Drug Discovery introduces Revvity's preclinical high content imaging services.

Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.

Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy

Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.


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