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Application Note
CRISPRsc: Pooled CRISPR screening with single-cell transcriptome resolution
This application note describes a pooled CRISPR screen with single-cell transcriptome resolution to link gene expression signature with drug response.
Application Note
CRISPR-Cas9 screening for target identification
Explore the power of whole-genome CRISPR-Cas9 screening in this application note.
Application Note
CRISPRa: Transcriptional upregulation screening with genome-wide CRISPR activation
This application note demonstrates transcriptional upregulation screening with genome-wide CRISPR activation.
Application Note
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening
Discover the advantages of a dual screen using CRISPRi and CRISPRa screening in parallel in this application note.
Application Note
CRISPRi: Transcriptional repression screening with genome-wide CRISPR interference
This application note demonstrates transcriptional regression screening with a novel whole-genome CRISPRi platform.
Flyer
Preclinical services reading list
Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Whitepaper
How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.
Application Note
Profiling compound effect on immune cells by combining ImmuSignature assays and LEGENDplex bead-based multiplex protein quantification
Explore Revvity's preclinical services for cell engineering and screening in our ebook.
Application Note
Development of AlphaLISA technology assays for the detection of neutralizing antibodies in human serum
We report here the development of two AlphaLISA functional assays, a cell-based and a biochemical assay, for the detection of neutralizing ADA in human serum samples.
Brochure
Signaling in the immune system - HTRF assays for oncology and inflammation
A summary of signaling pathways in the immune system.
Whitepaper
Deciphering the role of neutrophils in virus-induced respiratory disease
Preclinical imaging of neutrophilic response in viral infection with IVISense™ Neutrophil Elastase fluorescent probes.
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