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Case Study
NIH NCATS case study: using accelerated screening research for SARS-CoV-2 drug repurposing candidates
Find out how the NCATS team was able to quickly screen 3,384 molecular entities and narrow them down to a field of 25 quality "hits" capable of disrupting SARS-Cov-2 S1 protein:ACE2 receptor binding in this case study.
Application Note
Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
Product Info
Omni Bead Ruptor bead mill consumables overview marketing sheet
Omni Bead Ruptor bead mill consumables overview marketing sheet
Application Note
Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
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