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Brochure
The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.
Technical Note
Determining sensitivity of in vivo optical imaging systems
This technical note highlights the IVIS platforms minimal detectable radiance (MDR) and other features regarding the high sensitivity output of the platform
Flyer
LentiBOOST transduction enhancer
This flyer provides an overview of the LentiBOOST transduction enhancer technology.
Scientific Poster
One-Step Multiplex Knockout and CAR Integration in CAR-T Cells
This poster presents a novel approach for CAR-T cell engineering using Pin-point™ base editing, achieving simultaneous multiplex knockout and CAR insertion.
Scientific Poster
rAAV Manufacturing Optimization Using Design of Experiments
Explore the use of design of experiments (DoE) for optimizing plasmid ratios in rAAV manufacturing, improving yields and reducing production costs.
Scientific Poster
Image-Based CAR-T Cell Assays for Apoptosis and CAR Expression Monitoring
This poster introduces a new image-based method to monitor CAR expression and apoptosis in CAR-T cells, offering insights into cell viability post-gene delivery.
Whitepaper
ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.
Literature - Publication Review
The future of immunotherapy gets brighter with base editing
This literature review discusses how base editing technology addresses the shortcomings of other gene editing technologies for immunotherapy.
Whitepaper
Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.
Whitepaper
Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.
Whitepaper
Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.
Scientific Poster
A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.
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