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Technical Note
Improved high-content imaging of tissue sections
Technical note describing how to improve high-content imaging of tissue sections.
Application Note
Distinguishing cell types by phenotypic profiling of the nucleus
As nearly all screening approaches require a nuclear counterstain, phenotypic profiling of the nuclei can offer new insights on assays at no extra cost.
Literature - Publication Review
Morphological profiling of human T and NK lymphocytes by high-content imaging
The study in this publication review provides a foundation for the development of morphological profiling as a scalable approach to monitor the immune synapse (IS), primary lymphocyte responsiveness and microarchitecture.
Literature - Publication Review
Multifunctional mRNA-based CAR T-cells show promising anti-tumor activity against glioblastoma
Learn how researchers have evaluated the efficiency of mRNA-based multifunctional CAR T-cells against glioblastoma in vitro and in vivo.
Application Note
Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System
Application Note - Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System.
Literature - Publication Review
Imaging and gene editing approaches highlight important role of autophagy in controlling Mtb infection
Learn how researchers used CRISPR-Cas9 gene editing and high-content imaging approaches to explore the role of autophagy in controlling Mtb infection.
Case Study
A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
Literature - Publication Review
HCS Publication List
A selection of publications from 2022 and 2023 using Revvity HCS systems are featured here.
Literature - Publication Review
HCS featured publications for infectious disease
This provides a list of various HCS publications in the area of infectious disease (viral, parasitic, and bacterial).
Whitepaper
High content screening in three dimensions
This paper provides a recommended workflow for 3D HCS analysis, with a focus on reducing the 3D image analysis time by utilizing High Performance Computing.
Application Note
Phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes
Application note describing phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes using the Opera Phenix high-content screening system
Brochure
Opera Phenix Plus High-Content Screening System Brochure
Opera Phenix ® Plus high-content screening system designed for fast response analysis for sensitive confocal imaging.
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