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Scientific Papers
Modular Pin-point™ Base Editing for Multi-Target Efficiency
Detailing the modular capabilities of the Pin-point™ base editing platform, this poster examines its role in multi-gene targeting for streamlined cell therapy applications.
Scientific Poster
SMARTvector™ Multiplex shRNA for Enhanced Cell Therapy Safety
Explore the SMARTvector™ multiplex shRNA platform for safe, multi-target gene knockdown in cell therapy applications, offering new levels of therapeutic control and safety.
Literature - Publication Review
A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout
This literature review delves into an application of gene editing that achieves simultaneous knock-in and multiple gene knockout.
Webinar
Advancing Gene Editing Efficiency and Precision with the Pin-point™ Base Editing Platform
This webinar discusses how the Pin-point™ base editing platform can achieve more efficient and precise complex multiplex edits of cell lines, while decreasing the potential of unintended consequences.
Scientific Poster
Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.
Application Note
Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.
Brochure
The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.
Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Whitepaper
Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity
Whitepaper
CRISPR-Cas9 screening: a powerful approach to advance drug discovery
Find out about the potential of CRISPR-Cas9 screening for drug discovery in this white paper.
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