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Application Note
Developing novel tetraubiquitin substrates and AlphaLISA technology to provide next generation deubiquitinase assays
This application note presents novel biochemical DUB assays that use TUBEs to bind to tetraubiquitin substrates of at least three natural linkages. These assays, combined with Revvity’s AlphaLISA™ technology, allow for the measurement of protein interactions and large protein complexes in a no-wash, homogeneous assay.
Application Note
Detection of human matrix metalloproteinase 9 in complex sample matrices, a comparison of AlphaLISA and colorimetric ELISA immunoassays
This note compares two immunoassay technologies: ELISA (enzyme-linked immunosorbent assay) and AlphaLISA™ (amplified luminescent proximity-based homogeneous assay).
Infographic
Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Whitepaper
Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
Flyer
Cellometer Spectrum image cytometer flyer
Flyer summarizing the Cellometer Spectrum image cytometer.
Literature - Publication Review
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
Researchers used the IVIS Spectrum and IVISbrite D-luciferin substrate to investigate how a spleen-targeted DNA vaccine, delivered via RBC-hitchhiked nanoparticles, effectively induced robust neoantigen specific T cell responses in HCC.
Whitepaper
Leveraging next-generation cell line development technologies for cost-effective biotherapeutic applications
Reviewing the transformative innovations within the cell line development process to help improve biotherapeutics.
Whitepaper
Ex Vivo Functional Drug Testing of 3D Patient-Derived Cancer Cells Shows Promise for Personalized Medicine
Demonstrating how functional testing of 3D patient-derived cancer cells enables effective drug sensitivity testing.
Literature - Publication Review
Improving precision stratification using patient-derived model systems
Precision stratification using patient-derived model systems.
Whitepaper
An emerging therapeutic modality - RNA carves its path out of the paradigm
Learn more about several promising classes of RNA therapeutic, including RNAi, CRISPR, base editing, and mRNA vaccines, as well as the potential to combine RNA technologies with CAR-T.
Whitepaper
Gene editing of primary immune cells to aid next-generation cellular immunotherapies
Researchers have successfully deployed CRISPRa/i in primary human T cells, offering critical insights into the pathways required for cytokine regulation.
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