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Application Note
Evaluating the specificity of PD-1 and PD-L1 blocking antibodies using AlphaLISA human and mouse PD-1/PD-L1 binding kits
Find out how the AlphaLISA human/mouse PD-1/PD-L1 binding assays provide a fast, powerful, homogeneous platform for obtain binding potencies from potential novel drug candidates.
Application Note
AlphaLISA human IL-6 kit can quantify pyrogens in monocyte activation tests
Usefulness of the AlphaLISA IL-6 kit for the quantification of pyrogens and the ease of use of a homogeneous, wash-free assay with low sample volumes.
Application Note
Alpha technology: a fast and sensitive orthogonal approach to cell-based potency assays
Learn why Alpha technology is an ideal cell-free orthogonal system for potency assays.
Application Note
Development of pharmacokinetic (PK) assays for detecting biosimilars targeting TNF alpha using AlphaLISA
In this Application Note, AlphaLISA™ assays are used for detecting biosimilars targeting TNF alpha. Learn more.
Application Note
Streamline the HEK 293 HCP impurity quantification workflow with new, no-wash AlphaLISA HEK 293 Host Cell Protein Kit
Read our new HEK HCP application note to learn about HEK 293 HCP impurity quantification using AlphaLISA technology (link not available yet)
Product Note
Automated characterization of proteins and nucleic acids
Streamline your slab gel electrophoresis, while providing increased throughput and the data formats required for biotherapeutics and genomics workflows.
Technical Note
Biotin-free AlphaLISA assays for the detection of cytokines in PBMC supernatants
In this technical note, AlphaLISA biotin-free kits were used to detect and quantify the cytokines interleukin 2 (IL-2), tumor necrosis factor alpha (TNFα), interferon gamma (IFN-γ), and interleukin 6 (IL-6).
Application Note
Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
Application Note
Simultaneous detection of drug efficacy and toxicity by combining HTRF, AlphaLISA, or AlphaLISA SureFire Ultra with ATPlite
This application note demonstrates how compound’s mechanism of action and potential cytotoxic effects can be deciphered thanks to the combination of AlphaLISA™, HTRF™ or AlphaLISA™ SureFire® Ultra™ immunoassays with ATPlite™ 1step cell viability assay.
Application Note
FcRn binding assays using AlphaLISA and HTRF technologies
In this application note you will find information about how both AlphaLISA™ and HTRF™ assays can help to measure the relative affinities of therapeutic antibodies to FcRn.
Application Note
No-Wash IP1 assays are a powerful readout to characterize compounds modulating the FGFR signaling pathway in cancer drug research
This application note demonstrates that detecting the intracellular accumulation of IP1, mediated by FGFR-dependent activation of PLCγ1, can be a powerful alternative for characterizing compounds that modulate FGFR signaling in various cancer cell lines expressing FGFR1, FGFR2, and FGFR3.
Literature - Publication Review
HTRF and AlphaLISA assays bring clarity to extracellular matrix related fibrosis development
This note gathers publications that exemplify various applications of HTRF™ and AlphaLISA™ assays to advance fibrosis related research and shows how other researchers have harnessed these technologies to move their studies forward.
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