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Application Note
Optimization of complement-dependent cytotoxicity assay on OncoSignature cell lines
This application note provides insight into how our complement-dependent cytotoxicity assay can help drug screening efforts by leveraging our semi-automated screening platform and OncoSignature™ cell panel.
Guide
Immune cell compound screening compendium
This application compedium provides an overview of four immune cell compound screening applications using ImmuSignature™ assays.
Whitepaper
CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.
Scientific Poster
One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.
Whitepaper
Preclinical screening platforms for antibody-drug conjugate therapeutics
Learn more about ADCs and the role that screening can play to help advance the discovery process for ADC therapeutic candidates in this white paper.
Scientific Poster
Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Base Editing of Human Hematopoietic Stem and Progenitor Cells with the Pin-point™ platform
Learn why the Pin-point™ base editing platform is a valuable tool for the generation of advanced cell therapies using sensitive cell types.
Scientific Poster
Optimization of Modular Pin-point™ Base Editing with Type V CRISPR-Cas
This poster details advancements in the Pin-point™ base editing platform, focusing on modularity and efficiency improvements with Type V CRISPR-Cas effector applications in gene therapy.
Scientific Poster
Enhanced iPSC Editing with Minimal p53 Activation via Pin-point™
Focused on improving iPSC editing, this poster discusses reduced p53 pathway activation with Pin-point™ cytidine base editing, enhancing cell viability and therapeutic outcomes.
Scientific Poster
Custom gRNA Design and Efficiency Prediction in Pin-point™ Editing
This poster discusses the development of custom guide RNA (gRNA) design tools and efficiency prediction models, enhancing Pin-point™ base editing accuracy in gene therapy applications.
Scientific Poster
Advancements in Pin-point™ Base Editing for Targeted Gene Therapy
This poster showcases the latest improvements in the Pin-point™ base editing platform, emphasizing applications in targeted gene therapy for enhanced therapeutic outcomes.
Scientific Poster
Multi-Omic Analysis of Immune Cells Using Pin-point™ Base Editing
Presenting multi-omic analysis techniques for immune cells edited with Pin-point™, this poster uncovers insights into cell engineering outcomes in CAR-T therapies.
Scientific Poster
Development of a High-Efficiency RNA-Guided Base Editing System
Presenting a high-efficiency RNA-guided base editing platform, this poster explores increased precision in gene editing applications, suitable for cell therapy advancements.
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