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Preclinical services reading list
Selected publications that utilizes Revvity’s Preclinical Services to enhance scientific research and progress drug discovery.
Application Note
Target essentiality assay
This application note demonstrates Revvity’s target essentiality assay which indicates whether or not a specific gene is essential for survival and/or proliferation in a given cell line.
Whitepaper
How CRISPR-based functional genomics is transforming drug discovery
Exploring how functional genomics is used in preclinical drug discovery with target identification, drug response mechanisms, and in vivo tumor biology.
Webinar
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Discover automated high-throughput DNA extraction for large-scale genomic studies and benefit from expert experiences. Watch this webinar now!
Application Note
Profiling compound effect on immune cells by combining ImmuSignature assays and LEGENDplex bead-based multiplex protein quantification
Explore Revvity's preclinical services for cell engineering and screening in our ebook.
Case Study
A novel non-Invasive in vivo tool for the assessment of NASH
Visualizing and quantifying NASH in a preclinical in vivo imaging model using the IVIS Lumina Series III optical and Quantum GX2 microCT imaging systems.
Product Note
IVIS Lumina X5 product note
High-sensitivity 2D optical meets high-resolution x-ray with the IVIS Lumina X5 benchtop imaging system.
Whitepaper
Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.
Whitepaper
Non-invasive optical imaging for viral research and novel therapeutic and vaccine development
Non-invasive optical image using IVIS ® systems for pre-clinical viral research.
Literature - Publication Review
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Researchers use a clinically translatable cytokine delivery platform in an ovarian mouse model validated using IVIS® optical imaging and IVISbrite™ D-luciferin bioluminescent substrate.
Product Note
IVIS Lumina S5 product note
Flexible and sensitive 2D optical imaging in a benchtop format with the IVIS Lumina S5 system.
Article
Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging
Researchers discuss the rationalrationale behind utilizing various pre-clinical in vivo imaging techniques to explore the uptake of custom-designed nanomedicines at different stages of brain cancer.
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