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Optimizing AAV manufacturing: a scalable harvest protocol
As demand for recombinant AAV (rAAV) vectors continues to rise, scalable and efficient manufacturing processes are essential for advancing gene therapy.
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Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.
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Why using cell line-derived reference material is critical for reliable genetic testing in oncology
This white paper explains the importance of using cell line-derived reference materials for genetic testing in oncology.
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Epigenetic modifications and how they relate to cancer development and therapy
In this white paper, you’ll learn the general description of the three types of epigenetic modifications, how they play diverse roles in tumorigenesis and cancer progression, and the promising future of epigenetics in cancer.
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Antibody-based therapeutic modalities in oncology
Explore monoclonal antibody-based cancer therapeutics in this white paper, covering mechanism of action, development, and challenges.
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Cell-based assays: Purposeful screens for better results
Insights gained over the years through close interactions with researchers to provide the key elements to consider when setting up cell-based assays.
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Understanding the ‘how’ and ‘why’ of spectral unmixing
Understanding the “why” and “how” of using spectral unmixing in your in vivo imaging studies
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The role of in vivo imaging in drug discovery and development
Preclinical in vivo imaging helps to ensure that smart choices are made by providing go/no-go decisions and de-risking drug candidates early on, significantly reducing time to the clinic and lowering costs all while maximizing biological understanding.
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Guidance for ensuring your VICTOR Nivo multimode plate reader complies with 21 CFR Part 11
With specific reference to the relevant paragraphs of 21 CFR Part 11, this document describes how the tools within the VICTOR NivoTM Enhanced Security software facilitate compliance with this regulation.
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Genetically engineered PDX models as patient avatars in preclinical evaluation of acute leukemias
Identifying therapeutic targets using gene silencing techniques in PDX models
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Research spotlight: new therapeutic targets focusing on aberrant lipid metabolism in Alzheimer’s disease
This whitepaper explores new therapeutic targets focusing on Aberrant Lipid Metabolism in Alzheimer's Disease
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Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.
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