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Sugar with your protein? - Generation of a fucosylation-deficient CHO cell host to produce therapeutics with enhanced potency
Detailed overview of how CHO cells have been genetically modified to enable production of afucosylated antibodies with enhanced ADCC activity for improved biotherapeutics

Accelerating immuno-oncology therapeutic development: choosing the best preclinical model
Selecting the appropriate preclinical model for immuno-oncology therapeutic development.

Exploring current and future approaches for targeting KRAS
Get the latest insights on KRAS and see how it has switched from being an undruggable to a druggable cancer target

Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics

Precise cell engineering
Explore the advanced capabilities of the Pin-point™ base editing platform for multiplex gene editing and its application in T cells and iPSCs. Discover how CITE-Seq enables deeper insights into single-cell phenotyping and cell therapy development.

AAV vectors: Pursuing a one-time therapy for ocular diseases
Explore the latest advancements in gene therapy and its transformative impact on ocular health.

Innovative approaches for advancing genetic payload development
Discover the future of gene therapy in our white paper 'Innovative approaches for advancing genetic payload development.' Learn about the challenges and breakthroughs in gene editing, offering a glimpse into the evolving landscape of genetic medicine.

Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples

Achieving higher throughput for the bioanalysis of advanced biotherapeutics
With advanced biotherapeutics requiring characterization and stringent quality control, read how by assessing critical quality attributes early within cell line development you can improve your chances in clinic

Efficient multiplexed targeted gene editing as a strategy to generate improved CHO host cell lines for biotherapeutic manufacturing applications
Learn about Revvity’s capabilities to simultaneous edit genes using CRISPR-Cas9 that incorporates stringent genetic QC steps for comprehensive characterization.

Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic

Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.


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