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Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Literature - Publication Review
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
Researchers used the IVIS Spectrum and IVISbrite D-luciferin substrate to investigate how a spleen-targeted DNA vaccine, delivered via RBC-hitchhiked nanoparticles, effectively induced robust neoantigen specific T cell responses in HCC.
Literature - Publication Review
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
Researchers design an adeno-associated virus (AAV) 6 capsid that demonstrates efficiency in lung epithelial cell transduction in a mouse model validated using optical imaging.
Literature - Publication Review
Countering vascular calcification through mitochondrial phosphate transport inhibition in a CKD murine model
Researcher using in vivo imaging to study countering vascular calcification through mitochondrial phosphate transport inhibition in chronic kidney disease.
Literature - Publication Review
Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model
Literature - Publication Review
Deciphering the properties of neuronal nicotinic acetylcholine receptors using radiolabeled α-Bungarotoxin
Deciphering the Properties of Nicotinic Acetylcholine Receptors Using 125I-α-Bungarotoxin
Literature - Publication Review
Ultrasound imaging provides noninvasive 3D views into vascular changes in response to cancer therapy
Ultrasound imaging using the Vega® automated system provides noninvasive 3D views into vascular changes in response to cancer therapy.
Literature - Publication Review
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development
Dr. Kawaoka Yoshihiro, a world-renowned virologist uses the Quantum microCT system to study SARS-CoV-2 in Syrian hamster models.
Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
Optical imaging using the IVIS® Platform to evaluate a novel nanoparticle system for controlled liraglutide release in a diabetic mouse model.
Literature - Publication Review
Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
Researchers used the Opera Phenix® HCS and IVIS® preclicinal imaging system to evaluate engineered T-cells through epigenetic modulation showing the potential of improving the cytotoxic effects on solid tumors.
Literature - Publication Review
Improving precision stratification using patient-derived model systems
Precision stratification using patient-derived model systems.
Literature - Publication Review
In vivo imaging of influenza virus infection in immunized mice
Using the IVIS® in vivo imaging platform to quantifiy H1N1pmd09-Nluc influenza viral load in mice and demonstrated that human mAb administration has a protective or therapeutic effect in mice challenged with influenza virus.
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