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Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.
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NIH NCATS case study: using accelerated screening research for SARS-CoV-2 drug repurposing candidates
Find out how the NCATS team was able to quickly screen 3,384 molecular entities and narrow them down to a field of 25 quality "hits" capable of disrupting SARS-Cov-2 S1 protein:ACE2 receptor binding in this case study.
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Temporal tracking of an effective intervention in rodent liver fibrosis
Visualize, track, and quantify progression & regression of liver fibrosis using the Vega® non-invasive 3D ultrasound system.
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Automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice
Case study evaluated automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice.
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Using IVIS optical imaging of CRISPR/Cas9 engineered adipose tissue to study obesity prevention
Assessment of brown fat activation of CRISPR engineered adipose tissue in a mouse model using Revvity's IVIS® optical imaging platform.
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A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity
A Novel Mouse Model Using IVIS® Optical Imaging to Detect On-Target, Off-Tumor CAR-T Cell Toxicity.
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Improving the throughput of a neuroprotection assay using the opera phenix high content screening system
Download the case study to learn how primary neuron morphology is analyzed in a straightforward approach using Harmony® software and careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.
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Re-tooling anti-microbial research for the 21st century
Case study describing the analysis of bacterial phenotypes to investigate adaptive mechanisms of antimicrobial resistance and screening for novel alternatives.
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A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
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A workflow to characterize and benchmark human induced pluripotent stem cells
Case study describing a high-content imaging workflow to characterize and benchmark human induced pluripotent stem cells
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Phenotypic characterization of mitochondria in breast cancer cells using morphology and texture properties
This case study validates the use of STAR morphology and SER texture features to quantifiably characterize mitochondrial morphology and to detect changes induced by drug treatments.
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High-content analysis of drug-induced oligodendrocyte differentiation promoting remyelination in multiple sclerosis
Case study describing High-Content Analysis of Drug-Induced Oligodendrocyte Differentiation Promoting Remyelination in Multiple Sclerosis
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