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Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging
Researchers discuss the rationalrationale behind utilizing various pre-clinical in vivo imaging techniques to explore the uptake of custom-designed nanomedicines at different stages of brain cancer.
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Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
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Research spotlight interview: the role of biomarkers in drug discovery for neurodegenerative disease
Researcher takes a multidisciplinary approach in defining early biomarkers of dementia.
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cst-research-spotlight-qa-alves-opioids-bone-homogenization
Method development for toxicological analysis of synthetic opioids from bone.
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Top tips for effective gene silencing in 3D cultures
Discover how to achieve efficient gene knockdown in 3D cell cultures.
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Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
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Modular Pin-point™ Base Editing for Multi-Target Efficiency
Detailing the modular capabilities of the Pin-point™ base editing platform, this poster examines its role in multi-gene targeting for streamlined cell therapy applications.
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Top tips for elevating your single-cell sequencing experiments
Discover emerging strategies for some prevalent challenges within single-cell studies.
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Tackling Biofilm Formation
This article provides an overview of novel approaches to improve our understanding of biofilms and enhance the diagnosis and treatment of bacterial implant infections.
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Research spotlight interview: Combining expertise in 3D airway cell models with SARS-CoV-2 research
A study on the first interaction of SARS-CoV-2 with host respiratory tissues.
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Revolutionizing neurodegenerative disease research with brain-on-chip technology
The potential transformative impact of brain-on-chip technology on the field of neuroscience.
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Tackling Huntington's disease from all angles
Huntington's Disease research to better characterize early stages of the disease and discover new treatment therapies, while lending support to HD patients and families.
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