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Application Note
HMGB1, IL-1β and IL-18 assays used together to discriminate pyroptosis and necroptosis
This application note shows that the release of HMGB1 induced in the context of pyroptosis and necroptosis can be easily monitored with the HTRF® HMGB1 kit.
Application Note
Download your application note on fibrosis characterization
This note describes deep investigations of the molecular mechanisms involved in tissue fibrosis, and occurring in the major effector cell types.
Application Note
Download your application note on nuclear receptor ligand identification with HTRF
This application note illustrates the use of HTRF PPI reagents to easily build robust and convenient biochemical NR/ CoA recruitment assays.
Literature - Publication Review
Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model
Application Note
Noninvasive tracking of spleen volume in rodents using automated ultrasound imaging
Noninvasive tracking of spleen volume in cancer and lupus murine models using the Vega™ automated, hands-free, high-throughput ultrasound imaging system
Literature - Publication Review
HTRF and AlphaLISA solutions in inflammatory bowel diseases research
This note groups four scientific publications which spotlight the use of HTRF and Alpha solutions applied to IBD research.
Literature - Publication Review
Virology research solutions using HTRF Protein-Protein interaction assays
This literature review shows that various publications demonstrate the relevance of HTRF approaches to perform research and propose different assay formats suited for tackling viruses in several steps of their life cycle.
Literature - Publication Review
Strengthen cancer treatment search with HTRF™, AlphaLISA™, and DELFIA™-TRF kits
This note highlights two studies that used biochemical and cell-based assays to help characterize and develop new treatments to target Non-Small Cell Lung Carcinoma (NSCLC) and Soft Tissue Sarcomas (STS).
Literature - Publication Review
Literature review on solutions for investigating Huntington’s disease
This literature review shows how researchers have taken advantage of immunoassays to move their research forward. It features experiments and data from published studies that investigated new leads for Huntington’s disease drug discovery.
Application Note
Best practices for analyzing tumor xenografts
This technical note provides procedures and guidelines for performing HTRF phospho-protein assays on tumor xenografts, with a particular focus on the preparation of tumor lysates and working samples.
Literature - Publication Review
Expand your horizons with this literature review of multiple sclerosis research studies
Discover this literature review showing how scientists leverage immunoassays to move their research forward. Expand your horizons with experiments and data from published studies that investigate new leads for multiple sclerosis (MS) drug discovery.
Application Note
Download your protocol on CD4 T cells differentiation into Th17 cells
In this application note is reported a protocol for the isolation of mouse naïve CD4+ T-cells and their differentiation into T-Reg and Th-17 cells.
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