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Selective targeting of mHTT presents novel therapeutic approach to huntington's disease
Researchers have engineered zinc finger protein transcription factors (ZFP-TFs) to target the pathogenic CAG repeat and selectively lower mHTT as a therapeutic strategy.
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Solutions for virology research
Virology research solutions to enable virus monitoring, neutralization testing, as well as viral pathogenesis studies.
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Research spotlight interview: the role of biomarkers in drug discovery for neurodegenerative disease
Researcher takes a multidisciplinary approach in defining early biomarkers of dementia.
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Meet the scientist: uncovering the pathways dictating evolution of lung cancer heterogeneity
Understanding why tumors evolve from a single cell to a heterogenous tissue could direct the development of new therapies.
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Precision medicine research, for sharper decisions
Precision medicine can lead to sharper decision making through functional and molecular stratification.
Publication Icon   Literature - Publication Review
Expert interview: recapitulating the blood-brain barrier using in vitro hiPSC models in drug discovery
Better understand the blood-brain barrier for translational research and drug discovery in neurodegenerative diseases.
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Advancing biotherapeutic development with transposon-based technologies
Discover how to generate highly producing pools early on in your development workflow with transposon technology and accelerate time to clinic
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The evolving landscape of quality by design in biologics manufacturing
Implement QbD principles to meet safety, efficacy, and consistency challenges in biologics manufacturing
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Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.
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Expert interview: cancer resistance to immunotherapy
Understand the Mechanisms behind Cancer Resistance to Immunotherapy
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Sugar with your protein? - Generation of a fucosylation-deficient CHO cell host to produce therapeutics with enhanced potency
Detailed overview of how CHO cells have been genetically modified to enable production of afucosylated antibodies with enhanced ADCC activity for improved biotherapeutics
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Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics
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