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Whitepaper
Relevance of multiparametric screening to drug discovery efforts
This white paper explores the importance of multiparametric screening to drug discovery efforts
Application Note
Machine-learning prediction of drug mechanism of action from high-content cell painting images
This application note demonstrates how machine-learning and high-content imaging can be applied to predict drug mechanism of actions.
Guide
IVISense fluorescent probe selector guide for oncology research
IVISense™ fluorescent probe guide contains information on matching probe properties to biology & biomarker characteristics, case studies, recommended probes and more to help advance oncology research.
Whitepaper
Deciphering the role of neutrophils in virus-induced respiratory disease
Preclinical imaging of neutrophilic response in viral infection with IVISense™ Neutrophil Elastase fluorescent probes.
Flyer
Integrins as targets for immunotherapy
Better understand integrins role in immuno-oncology in vivo with IVISense Integrin Receptor NIR fluorescent probes designed for in vivo imaging studies.
Application Note
Cell labeling and tracking in vivo using IVISense NIR fluorescent dyes
Track mammalian cells including stem cells, T-cells, macrophages and more in vivo with IVISense™ (VivoTrack) fluorescent labeling dye
Flyer
Best practices for designing an effective in vivo fluorescence imaging study
Best practices for designing an effective in vivo fluorescence imaging study.
Literature - Publication Review
SVEP1 as a regulator of GPCR-mediated vasoconstriction
This literature review describes how scientists uncovered multifunctional roles of SVEP1, a known contributor to cardiovascular disease.
Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
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