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Applications of In Vivo bioluminescence imaging for SARS-CoV-2
Scientists utilize non-invasive in vivo bioluminescence imaging to study SARS-CoV-2 progression, immune response and drug therapies.

Automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice
Case study evaluated automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice.

Ultrasound imaging provides noninvasive 3D views into vascular changes in response to cancer therapy
Ultrasound imaging using the Vega® automated system provides noninvasive 3D views into vascular changes in response to cancer therapy.

Countering vascular calcification through mitochondrial phosphate transport inhibition in a CKD murine model
Researcher using in vivo imaging to study countering vascular calcification through mitochondrial phosphate transport inhibition in chronic kidney disease.

IVIS Spectrum 2 platform - illumination in focus
Discover the next generation in preclinical optical imaging, the IVIS Spectrum 2 and IVIS SpectruCT 2 systems.

Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.

Improving engineered T cell efficacy for treating solid tumors through epigenetic modulation
Researchers used the Opera Phenix® HCS and IVIS® preclicinal imaging system to evaluate engineered T-cells through epigenetic modulation showing the potential of improving the cytotoxic effects on solid tumors.

A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity
A Novel Mouse Model Using IVIS® Optical Imaging to Detect On-Target, Off-Tumor CAR-T Cell Toxicity.

Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging
Researchers discuss the rationalrationale behind utilizing various pre-clinical in vivo imaging techniques to explore the uptake of custom-designed nanomedicines at different stages of brain cancer.

In vivo imaging of influenza virus infection in immunized mice
Using the IVIS® in vivo imaging platform to quantifiy H1N1pmd09-Nluc influenza viral load in mice and demonstrated that human mAb administration has a protective or therapeutic effect in mice challenged with influenza virus.

Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors
Using the IVIS® Spectrum non-invasive preclinical optical system to quantify tumor-specific T cells responses in NFAT-luciferase transgenic mice.

Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.


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