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Publication Icon   Literature - Publication Review
Clinically translatable cytokine delivery platform for eradication of intraperitoneal tumors
Researchers use a clinically translatable cytokine delivery platform in an ovarian mouse model validated using IVIS® optical imaging and IVISbrite™ D-luciferin bioluminescent substrate.
Publication Icon   Literature - Publication Review
Applications of In Vivo bioluminescence imaging for SARS-CoV-2
Scientists utilize non-invasive in vivo bioluminescence imaging to study SARS-CoV-2 progression, immune response and drug therapies.
Publication Icon   Literature - Publication Review
Tumor-targeting nanoparticles for enhanced PROTAC delivery
This publication review highlights how researchers using the IVIS Lumina III optical imaging system and Cellometer cell counter to study the potential of tumor-targeting nanoparticles to significantly enhance PROTAC delivery.
Product Note Icon   Product Note
VivoJect - Targeted injection of cells and drug therapies
This product note highlights the VivoJect image guided injection system for targeted delivery of cells and therapies
Publication Icon   Literature - Publication Review
DNA origami elevates the design of multispecific antibodies as cancer therapeutic agents
Publication review highlighting the use of the IVIS™ Lumina X5 optical imaging system and BioLegend Antibodies describe programmable T cell engagers (PTEs), a novel class of agents created with DNA origami, a nanotechnology that allows the precise spatial arrangement of biomolecules. When combined with antibodies, this approach holds great promise to develop specific and effective biomedical nanotherapies for diseases like cancer.
Publication Icon   Literature - Publication Review
Spleen-targeted neoantigen DNA vaccine for personalized immunotherapy of hepatocellular carcinoma
Researchers used the IVIS Spectrum and IVISbrite D-luciferin substrate to investigate how a spleen-targeted DNA vaccine, delivered via RBC-hitchhiked nanoparticles, effectively induced robust neoantigen specific T cell responses in HCC.
Case Study Icon   Case Study
Temporal tracking of an effective intervention in rodent liver fibrosis
Visualize, track, and quantify progression & regression of liver fibrosis using the Vega® non-invasive 3D ultrasound system.
Case Study Icon   Case Study
Automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice
Case study evaluated automated ultrasound for non-invasive in vivo evaluation of liver disease progression in mice.
Publication Icon   Literature - Publication Review
Ultrasound imaging provides noninvasive 3D views into vascular changes in response to cancer therapy
Ultrasound imaging using the Vega® automated system provides noninvasive 3D views into vascular changes in response to cancer therapy.
Publication Icon   Literature - Publication Review
Countering vascular calcification through mitochondrial phosphate transport inhibition in a CKD murine model
Researcher using in vivo imaging to study countering vascular calcification through mitochondrial phosphate transport inhibition in chronic kidney disease.
Brochure Icon   Brochure
IVIS Spectrum 2 platform - illumination in focus
Discover the next generation in preclinical optical imaging, the IVIS Spectrum 2 and IVIS SpectruCT 2 systems.
Case Study Icon   Case Study
Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.
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