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Whitepaper Icon   Whitepaper
Relevance of multiparametric screening to drug discovery efforts
This white paper explores the importance of multiparametric screening to drug discovery efforts
Application Note Icon   Application Note
Machine-learning prediction of drug mechanism of action from high-content cell painting images
This application note demonstrates how machine-learning and high-content imaging can be applied to predict drug mechanism of actions.
Brochure Icon   Brochure
IVIS Spectrum 2 platform - illumination in focus
Discover the next generation in preclinical optical imaging, the IVIS Spectrum 2 and IVIS SpectruCT 2 systems.
Case Study Icon   Case Study
Assessment of MYC-driven progression of small cell lung cancer
Researchers at Huntsman Cancer Center use GEMM and the Quantum microCT system for evaluating small cell lung cancer.
Whitepaper Icon   Whitepaper
Dual NIR imaging of β-Amyloid plaques and Tau tangles provides potential insights into Alzheimer’s disease
The use of Dual NIR Imaging of β-Amyloid Plaques and Tau Tangles to provide Potential Insights into Alzheimer’s Disease
Publication Icon   Literature - Publication Review
SVEP1 as a regulator of GPCR-mediated vasoconstriction
This literature review describes how scientists uncovered multifunctional roles of SVEP1, a known contributor to cardiovascular disease.
Whitepaper Icon   Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note Icon   Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note Icon   Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Publication Icon   Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Whitepaper Icon   Whitepaper
Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity
Whitepaper Icon   Whitepaper
CRISPR-Cas9 screening: a powerful approach to advance drug discovery
Find out about the potential of CRISPR-Cas9 screening for drug discovery in this white paper.
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