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Technical Note
Guidelines for optimizing tyrosine phosphorylation detection: Effective use of pervanadate in kinase small molecule inhibitors studies
This technical note explores how pervanadate enhances tyrosine phosphorylation detection, enabling clearer insights into kinase activity and inhibitor efficacy in drug discovery research.
Application Note
Excellent sensitivity from the EnVision Nexus multimode plate reader for AlphaLISA detection
This application note demonstrates the AlphaLISA detection capabilities of the EnVision Nexus and compares it to the EnVision 2105.
Whitepaper
Complete gene therapy review in a single industry report
A single Industry Report in collaboration with Labiotech provides a complete review of gene therapy including market trends, current challenges and a glimpse to the future.
Application Note
Utilizing AlphaLISA technology to screen for inhibitors of the CTLA-4 immune checkpoint
In this Application Note, AlphaLISA® assays are used for screening novel CTLA-4 blocking drugs. Learn more.
Case Study
NIH NCATS case study: using accelerated screening research for SARS-CoV-2 drug repurposing candidates
Find out how the NCATS team was able to quickly screen 3,384 molecular entities and narrow them down to a field of 25 quality "hits" capable of disrupting SARS-Cov-2 S1 protein:ACE2 receptor binding in this case study.
Application Note
CDK signaling: Investigate CDK4/6 inhibition in breast cancer cell lines with HTRF immunoassays
Learn how to analyze the inhibition of CDK4 and CDK9 in breast cancer using no-wash immunoassays.
Whitepaper
Applying functional genomics strategies to high-content phenotypic screening
Explore cutting-edge functional genomics and high-content phenotypic screening in drug discovery. Download our whitepaper to learn about innovative techniques, best practices, and strategies for leveraging high-content imaging methods like cell painting to advance your research. Unlock the potential of genomic profiling and morphological analysis for therapeutic interventions
Whitepaper
Accelerating immuno-oncology therapeutic development: choosing the best preclinical model
Selecting the appropriate preclinical model for immuno-oncology therapeutic development.
Whitepaper
Eyes on synaptotagmin 7 (SYT7) in synaptic function and neuroplastic health for cognitive decline
Researcher, Dr. Jason Vevea, describes the role of synaptotogmin 7 in the synaptic vesicle cycle and the experimental steps taken to discover that SYT7 supports asynchronous release, short-term synaptic plasticity, and synaptic vesicle replenishment.
Application Note
HTRF platform for anticancer drug discovery: from 2D and 3D cell cultures to xenograft models
Learn how to analyze cell signaling pathways on in vitro and in vivo sample types routinely used in the anticancer drug discovery process.
Guide
Unlocking insights with AlphaLISA anti-drug antibodies detection assays
Unlock ADA insights with AlphaLISA technology.
Application Note
Advancing K-Ras Targeted Therapies with Innovative Detection Methods
Explore our application note on innovative K-Ras detection methods using the HTRF™ immunoassay, advancing research in K-Ras targeted cancer therapies.
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