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Literature - Publication Review
Imaging and gene editing approaches highlight important role of autophagy in controlling Mtb infection
Learn how researchers used CRISPR-Cas9 gene editing and high-content imaging approaches to explore the role of autophagy in controlling Mtb infection.
Case Study
A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
Technical Note
A scalable and reproducible workflow for high-content analysis of cytotoxic effects in RASTRUM 3D cell cultures
Explore our Technical Note on a scalable workflow for high-content cytotoxicity analysis in 3D cell cultures. Discover reproducible 3D model creation, tailored microenvironment techniques, and enhanced imaging methods for accurate drug testing.
Literature - Publication Review
Improving precision stratification using patient-derived model systems
Precision stratification using patient-derived model systems.
Whitepaper
Therapeutic targeting of the tumor microenvironment
Understanding How Tumor and Host Cells Interact to Support Tumor Development and Therapeutic Resistance
Article
Research spotlight interview: Combining expertise in 3D airway cell models with SARS-CoV-2 research
A study on the first interaction of SARS-CoV-2 with host respiratory tissues.
Application Note
Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
Literature - Publication Review
Unlocking the potential of cancer immunotherapy: Overcoming the challenges of 3D immune cell killing assays
Explore several successful assay setups that utilize various analysis technologies to study the antitumor functions of immunotherapies in a 3D environment.
Whitepaper
High-throughput approaches to overcome antimicrobial resistance - part 1
The use of machine learning algorithms to predict how an organism is going to behave in response to an antimicrobial.
Whitepaper
High content screening in three dimensions
This paper provides a recommended workflow for 3D HCS analysis, with a focus on reducing the 3D image analysis time by utilizing High Performance Computing.
Application Note
Phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes
Application note describing phenotypic analysis of hypertrophy in human iPSC-derived cardiomyocytes using the Opera Phenix high-content screening system
Literature - Publication Review
Developing a phenotypic in vitro model for progression of liver steatosis
A recent study developed a model of hepatic steatosis in functional human induced pluripotent stem cell-derived hepatocytes (hiPSC-Hep).
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