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Technical Note
Improved high-content imaging of tissue sections
Technical note describing how to improve high-content imaging of tissue sections.
Application Note
Distinguishing cell types by phenotypic profiling of the nucleus
As nearly all screening approaches require a nuclear counterstain, phenotypic profiling of the nuclei can offer new insights on assays at no extra cost.
Literature - Publication Review
Morphological profiling of human T and NK lymphocytes by high-content imaging
The study in this publication review provides a foundation for the development of morphological profiling as a scalable approach to monitor the immune synapse (IS), primary lymphocyte responsiveness and microarchitecture.
Literature - Publication Review
Multifunctional mRNA-based CAR T-cells show promising anti-tumor activity against glioblastoma
Learn how researchers have evaluated the efficiency of mRNA-based multifunctional CAR T-cells against glioblastoma in vitro and in vivo.
Application Note
Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System
Application Note - Fast Kinetic Calcium Flux Imaging Using the Opera Phenix Plus High-Content Screening System.
Literature - Publication Review
Imaging and gene editing approaches highlight important role of autophagy in controlling Mtb infection
Learn how researchers used CRISPR-Cas9 gene editing and high-content imaging approaches to explore the role of autophagy in controlling Mtb infection.
Case Study
A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
Application Note
Analyzing ERK signal transduction in live cells using a FRET-based biosensor
Application note describing analysis of ERK signal transduction in live cells using a FRET-based biosensor with the Operetta CLS high-content analysis system.
Case Study
B cell selection and therapeutic antibody characterization using the Operetta high content imaging system
This case study illustrates how Revvity’s high content imaging solutions are enabling therapeutic antibody development.
Technical Note
3D volumetric and zonal analysis of solid spheroids
Technical note describing how to image and analyze solid spheroids in 3D.
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
Technical Note
Clearing strategies for 3D spheroids
In this technical note, we compare optical clearing strategies for 3D spheroids and demonstrate how to increase imaging depth in 3D spheroids by a factor of 4.
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