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Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Application Note
Analyzing ERK signal transduction in live cells using a FRET-based biosensor
Application note describing analysis of ERK signal transduction in live cells using a FRET-based biosensor with the Operetta CLS high-content analysis system.
Case Study
B cell selection and therapeutic antibody characterization using the Operetta high content imaging system
This case study illustrates how Revvity’s high content imaging solutions are enabling therapeutic antibody development.
Application Note
Analysis of mitochondrial dynamics in human iPSC-derived neurons using the Operetta CLS High-Content Analysis System
Learn how to investigate mitochondrial dynamics in human IPSC-derived neurons using the Operetta CLS high-content analysis system in this application note.
Application Note
Cytotoxicity studies on 3D primary liver microtissues
Application note describing Cytotoxicity Studies on 3D Primary Liver Microtissues using high-content analysis.
Technical Note
3D volumetric and zonal analysis of solid spheroids
Technical note describing how to image and analyze solid spheroids in 3D.
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
Technical Note
Clearing strategies for 3D spheroids
In this technical note, we compare optical clearing strategies for 3D spheroids and demonstrate how to increase imaging depth in 3D spheroids by a factor of 4.
Application Note
Phenotypic analysis of CRISPR-Cas9 cell-cycle knockouts using cell painting
Learn about our harmonized workflow for morphological profiling of CRISPR-Cas9-mediated knockouts using cell painting in this Application Note.
Application Note
Kinetic analysis of calcium flux activity in human iPSC-derived neurons using the Opera Phenix Plus system
Application note for fast kinetic imaging using HCS to visualize and evaluate spontaneous calcium flux activity in single human iPSC-derived neurons
Guide
Harness the power of 3D cell model imaging
In our guide, learn how to harness the power of 3D cell model imaging.
Technical Note
How to perform long term live cell imaging in a high‑content analysis system
Technical note describing How to Perform Successful Long-Term Live-Cell Imaging in a High-Content Analysis or Screening System
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