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Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Literature - Publication Review
Inhibiting interleukin 11 signaling reduces and reverses many dangerous effects of NAFLD/NASH in mouse models
Study demonstrating that inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of NASH
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
Guide
Harness the power of 3D cell model imaging
In our guide, learn how to harness the power of 3D cell model imaging.
Technical Note
How to perform long term live cell imaging in a high‑content analysis system
Technical note describing How to Perform Successful Long-Term Live-Cell Imaging in a High-Content Analysis or Screening System
Application Note
Phenotypic profiling of autophagy using high content profiler
Using an autophagy assay as an example, this study describes the validation of a phenotypic image and data analysis workflow.
Case Study
Improving the throughput of a neuroprotection assay using the opera phenix high content screening system
Download the case study to learn how primary neuron morphology is analyzed in a straightforward approach using Harmony® software and careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.
Literature - Publication Review
Morphological profiling of human T and NK lymphocytes by high-content imaging
The study in this publication review provides a foundation for the development of morphological profiling as a scalable approach to monitor the immune synapse (IS), primary lymphocyte responsiveness and microarchitecture.
Literature - Publication Review
Multifunctional mRNA-based CAR T-cells show promising anti-tumor activity against glioblastoma
Learn how researchers have evaluated the efficiency of mRNA-based multifunctional CAR T-cells against glioblastoma in vitro and in vivo.
Literature - Publication Review
Imaging and gene editing approaches highlight important role of autophagy in controlling Mtb infection
Learn how researchers used CRISPR-Cas9 gene editing and high-content imaging approaches to explore the role of autophagy in controlling Mtb infection.
Case Study
A scalable method to monitor protein levels and localizations in cells
Pooled protein tagging, cellular imaging, and in-situ sequencing to identify cellular response to drug treatment.
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