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Literature - Publication Review
Inhibiting interleukin 11 signaling reduces and reverses many dangerous effects of NAFLD/NASH in mouse models
Study demonstrating that inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of NASH
Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Literature - Publication Review
Developing a phenotypic in vitro model for progression of liver steatosis
A recent study developed a model of hepatic steatosis in functional human induced pluripotent stem cell-derived hepatocytes (hiPSC-Hep).
Case Study
A workflow to characterize and benchmark human induced pluripotent stem cells
Case study describing a high-content imaging workflow to characterize and benchmark human induced pluripotent stem cells
Literature - Publication Review
Artemisinins target GABAA receptor signaling and impair α cell identity
Artemisinins Target GABA Receptor Signaling and Impair α Cell Identity encouraging α cells to convert into insulin-producing β-like cells.
Application Note
A multiparametric live-cell cytotoxicity analysis using the Operetta High-content Analysis System
An in vitro cytotoxicity approach using HepG2 cells, which are used as an effective indicator of the human hepatotoxicity potential of test compounds.
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Technical Note
High-content imaging of brain-on-chip microfluidic devices using PreciScan intelligent acquisition.
In collaboration with ETAP-Lab, this technical note demonstrates automated image acquisition of brain-on-chip microfluidic devices for neuronal research.
eBook
Upscaling organoid research for sharper biological insights
To scale up, standardize and achieve greater biological insights, researchers need to rely on automation and multi-dimensional datasets.
Infographic
Deeper insights from your 3D cell model imaging
Infographic describing tools and strategies to get the most out of your 3D cell model imaging and analysis workflows.
Technical Note
Nuclei segmentation on brightfield images using a pre-trained Artificial Intelligence (AI) model
Technical note describing the use of Phenologic.AI software module, for Signals Image Artist and Harmony image analysis software, for nuclei segmentation of brightfield images.
Application Note
Label-free analysis of cardiomyocyte beating using the Opera Phenix Plus System
Learn how to reliable quantify cardiomyocyte beating frequency using the Opera Phenix Plus high-content screening system in this application note.
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