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Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Technical Note
3D volumetric and zonal analysis of solid spheroids
Technical note describing how to image and analyze solid spheroids in 3D.
Technical Note
Clearing strategies for 3D spheroids
In this technical note, we compare optical clearing strategies for 3D spheroids and demonstrate how to increase imaging depth in 3D spheroids by a factor of 4.
Application Note
Kinetic analysis of calcium flux activity in human iPSC-derived neurons using the Opera Phenix Plus system
Application note for fast kinetic imaging using HCS to visualize and evaluate spontaneous calcium flux activity in single human iPSC-derived neurons
Technical Note
Opera Phenix High-Content Screening System: Improved 3D imaging
Technical Note describing how imaging of 3D cell models is improved using the Opera Phenix High-Content Screening System
Case Study
Improving the throughput of a neuroprotection assay using the opera phenix high content screening system
Download the case study to learn how primary neuron morphology is analyzed in a straightforward approach using Harmony® software and careful assay optimization can increase throughput, and minimize the data burden, without compromising assay performance.
Case Study
Re-tooling anti-microbial research for the 21st century
Case study describing the analysis of bacterial phenotypes to investigate adaptive mechanisms of antimicrobial resistance and screening for novel alternatives.
Whitepaper
Phenotypic drug discovery with high content screening
High content screening, a powerful approach to phenotypic drug discovery that leverages the rich information available in the image-based screens.
Technical Note
The benefits of water immersion lenses for high-content screening
This technical note explains why the choice of objective lens is critical for high-content screening.
Technical Note
Opera Phenix Plus high-content screening system: crosstalk suppression
Technical note describing how fluorescent crosstalk is suppressed by the Opera Phenix Plus high-content screening system.
Technical Note
Improved high-content imaging of tissue sections
Technical note describing how to improve high-content imaging of tissue sections.
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