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Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Whitepaper
Addressing the challenges of bispecific antibody characterization with high-throughput platforms
With the complexities of bispecific antibody development and characterization explore the binding assays and technology through real-world examples
Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Technical Note
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Quantifying TNFR1 in both soluble and membrane bound form using AlphaLISA technology
Technical Note
Quantitative analysis of lysine 36 demethylation with AlphaLISA
This technical note provides details on how the AlphaLISA immunodetection assay quantifies the demethylation of a biotinylated Histone H3 (21-44) peptide that is tri-methylated at lysine 36
Technical Note
AlphaLISA Acetyl‑Histone H3 lysine 9 (H3K9ac) cellular assay
This technical note provides information on how the AlphaLISA immunodetection assay detects variations in acetylated histone H3 lysine 9 (H3K9ac) levels within cellular extracts
Technical Note
Assessing AST released in a cell culture model of liver toxicity using AlphaLISA
In this technical note, we showcase the utility and advantages of using AlphaLISA assays to identify and quantify AST protein levels in cellular lysate and supernatant from a human hepatoma cell line
Technical Note
AlphaLISA for biomarkers in urine: Measuring the renal tubular injury indicator, β2-microglobulin
In this study, AlphaLISA™ technology is demonstrated for the first time in the complex matrix of urine, and is shown to detect the renal tubular injury marker Beta2-microglobulin (β2-microglobulin), in urine at a sensitivity
Whitepaper
ImmuSignature™ MLR: Rapid high-throughput assessment of therapeutic immunogenicity
This white paper describes how a rapid immunogenicity assessment screening can provide invaluable support for IND applications.
Whitepaper
Assessing the epigenetics of T cell exhaustion using CRISPR screens
Explore the epigenetics of T cell exhaustion and practical techniques to assess immune cell epigenetic regulators using CRISPR screens.
Application Note
Rapid screening of novel therapeutics by ImmuSignature™ T cell activation assay
This application note describes the development of a robust T cell activation assay to assess the impact of novel therapeutics on T cell function.
Application Note
Optimization of complement-dependent cytotoxicity assay on OncoSignature cell lines
This application note provides insight into how our complement-dependent cytotoxicity assay can help drug screening efforts by leveraging our semi-automated screening platform and OncoSignature™ cell panel.
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