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Whitepaper
Murine NASH model could provide insights into NASH development and progression
Researchers explore a multidisciplinary approach to addressing current NAFLD and NASH challenges.
Article
Busting high-content imaging myths
High-content imaging has become a cornerstone of life science research, providing valuable insights into cellular function and drug responses. However, as with any advanced technology, misconceptions and myths can emerge. In this article, we’ll debunk some of the most common myths surrounding high-content imaging, shedding light on its true strengths and limitations.
Application Note
Analysis of mitochondrial dynamics in human iPSC-derived neurons using the Operetta CLS High-Content Analysis System
Learn how to investigate mitochondrial dynamics in human IPSC-derived neurons using the Operetta CLS high-content analysis system in this application note.
Application Note
Cytotoxicity studies on 3D primary liver microtissues
Application note describing Cytotoxicity Studies on 3D Primary Liver Microtissues using high-content analysis.
Literature - Publication Review
Developing a phenotypic in vitro model for progression of liver steatosis
A recent study developed a model of hepatic steatosis in functional human induced pluripotent stem cell-derived hepatocytes (hiPSC-Hep).
Case Study
A workflow to characterize and benchmark human induced pluripotent stem cells
Case study describing a high-content imaging workflow to characterize and benchmark human induced pluripotent stem cells
Literature - Publication Review
Artemisinins target GABAA receptor signaling and impair α cell identity
Artemisinins Target GABA Receptor Signaling and Impair α Cell Identity encouraging α cells to convert into insulin-producing β-like cells.
Case Study
High-content analysis of drug-induced oligodendrocyte differentiation promoting remyelination in multiple sclerosis
Case study describing High-Content Analysis of Drug-Induced Oligodendrocyte Differentiation Promoting Remyelination in Multiple Sclerosis
Literature - Publication Review
Inhibiting interleukin 11 signaling reduces and reverses many dangerous effects of NAFLD/NASH in mouse models
Study demonstrating that inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of NASH
eBook
Upscaling organoid research for sharper biological insights
To scale up, standardize and achieve greater biological insights, researchers need to rely on automation and multi-dimensional datasets.
Application Note
Multi-parametric high-throughput analysis of hepatotoxicity using a 3D primary liver cell culture model
The creation of an advanced 3D primary human hepatocyte (PHH) model using the RASTRUM platform that seamlessly integrates with Revvity’s HTS technologies.
Technical Note
3D volumetric and zonal analysis of solid spheroids
Technical note describing how to image and analyze solid spheroids in 3D.
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