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Application Note
Phenotype discrimination using the PhenoVue cell painting and multi-organelle staining kits
In this study, we analyzed the phenotypes induced by a set of 15 reference compounds using both the PhenoVue cell painting kit and the PhenoVue multi-organelle staining kit to compare phenotypic discrimination results of the two assays.
Technical Note
Expanding imaging multiplexing capabilities with PhenoVue Fluor 400LS - Phalloidin
This technical note offers tips and best practices relating to fluorescent signal quality using PhenoVue Fluor 400LS Phalloidin stain.
Application Note
Orthogonal validation of CRISPRCas9 and siRNA generated phenotypes using cell painting
Investigate cell cycle regulation through AURKB, GMNN, and PLK1 proteins. Learn how CRISPR-Cas9 and siRNA techniques, combined with high-content imaging on the Opera Phenix™ Plus, reveal their roles in cell division and genomic stability.
Infographic
Cell painting: from images to innovation
Learn everything you need to know about cell painting, including what it is, how it works, and what you need to get started.
Whitepaper
Cell painting - a cellular imaging and machine learning approach to drug discovery
Cell painting solutions from Revvity offer powerful phenotypic high-content screening methods that help to accelerate drug discovery by delivering more predictive data.
Application Note
Cell painting for phenotypic screening
Application note describing how to set-up a cell painting assay.
Whitepaper
Guidance for ensuring your EnVision multimode plate reader complies with 21 CFR Part 11
Download this document and learn how the tools within Enhanced Security software for the EnVision plate reader can help support 21 CFR Part 11 compliance with access levels, data security, and a comprehensive audit trail of user actions
Application Note
Automation of tissue homogenization in protein analysis workflows using the Omni LH96 automated workstation
Benchmarking data and performance Omni LH 96 automated homogenizer workstation on tissues for protein expression in drug discovery and development.
Application Note
High throughput homogenization and DNA extraction from staple crops
Streamlined plant DNA extraction with bead mill homogenization
Application Note
Evaluation of drug selectivity and efficacy using PROTACs in a 3D co-culture spheroid model
The aim of this study was to evaluate the efficacy and selectivity of SJF1528, a pan-EGFR PROTAC, and MS39, a mutant-specific EGFR L858R PROTAC, while exploring the use of both high-content imaging and no-wash HTRF immunoassays in encapsulated 3D spheroid models.
Application Note
High-throughput mosquito DNA extraction and PCR analysis on the Omni Bead Ruptor 96 bead mill homogenizer
High-throughput mosquito DNA extraction and PCR analysis using bead-beating tubes and well-plate homogenizer
Application Note
High-throughput lysis of E. coli for multiple analytes using the Omni Bead Ruptor 96 bead mill homogenizer
Omni Bead Ruptor 96 enhances bacterial lysis and recovery of DNA, RNA, and proteins for high-throughput, well-plate sample homogenization and lysis
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