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Achieving CAR-T cell generation in a single intervention using a multiplex base editing system
In this poster, we highlight an example configuration of the Pin-point technology for the streamlined generation of allogeneic CAR-T cells and hypoimmunogenic iPSCs.

Increasing the targeting scope and precision of next-generation gene editing technology
In this application note, we demonstrate the Pin-point™ base editing system as a novel nucleaseagnostic modular platform for increasing the targeting scope and precision of next-generation gene editing technology.

CRISPR-derived base editing technology: The what, the how, and the why
This white paper provides a comprehensive guide to base editing, including what it is, how it works and applications.

One-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform
Discover one-step generation of allogeneic CAR-T cells by simultaneous multiplex knockout and site-specific transgene integration with the Pin-point™ base editing platform.

The Pin-point™ platform: A novel modular base editing system
This presentation provides an overview of the Pin-point base editing platform by describing its key benefits, how it works, and supporting data.

One-step engineering of allogeneic cell therapies with Pin-point base editing platform and an AI-engineered Cas enzyme
This scientific poster describes a one-step process to engineer allogeneic cell therapies with the Pin-point base editing platform and an AI-engineered Cas enzyme.

A breakthrough aptamer-mediated base editing platform for simultaneous knock-in and multiple gene knockout
This literature review delves into an application of gene editing that achieves simultaneous knock-in and multiple gene knockout.

Advancements in Pin-point™ Base Editing for Targeted Gene Therapy
This poster showcases the latest improvements in the Pin-point™ base editing platform, emphasizing applications in targeted gene therapy for enhanced therapeutic outcomes.

The future of immunotherapy gets brighter with base editing
This literature review discusses how base editing technology addresses the shortcomings of other gene editing technologies for immunotherapy.

Base editing and stem-cell based therapies
This white paper explores how base editing is advancing iPSCs in the fields of basic science, regenerative medicine and immunotherapy.

Addressing the challenges in solid tumor therapy with base editing
Read this white paper to learn about how base editing is helping to address key challenges in immunotherapies for solid tumors.

A single-step process for engineering hypoimmunogenic pluripotent stem cells with the Pin-point™ platform
Learn about the utility of the Pin-point™ base editing platform for the engineering of allogeneic PSCs.


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