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Whitepaper
Relevance of multiparametric screening to drug discovery efforts
This white paper explores the importance of multiparametric screening to drug discovery efforts
Brochure
CHOSOURCE expression platform
Helping you confront biotherapeutic challenges with a robust CHO expression platform without constraints.
Whitepaper
Maximizing returns in biotherapeutic investment: Financial considerations for expression systems
Helping examine the key economic factors when selecting expression systems that impact quality, quantity, and cost-effectiveness for biotherapeutic production.
Application Note
Machine-learning prediction of drug mechanism of action from high-content cell painting images
This application note demonstrates how machine-learning and high-content imaging can be applied to predict drug mechanism of actions.
Application Note
Streamlining the development of bispecific antibodies from expression to quality assessment with Revvity’s biotherapeutic workflow solutions
Expression and characterization of bispecific antibodies with a combination of CHOSOURCE TnT Transposon Technology and LabChip to streamline biotherapeutic workflows
Whitepaper
Harnessing cell line engineering to enhance biotherapeutics
Exploring the next-generation genome editing tools that are helping drive the success of monoclonal antibodies as biotherapeutics
Literature - Publication Review
SVEP1 as a regulator of GPCR-mediated vasoconstriction
This literature review describes how scientists uncovered multifunctional roles of SVEP1, a known contributor to cardiovascular disease.
Whitepaper
Generating a clonal HAP1LIG4(-) Cas9(+) cell line – an expert interview
An interview with Dr. Gerety, the Sanger Institute on generating a new HAP1 cell line and how it can help advance scientific discovery.
Application Note
Effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in high-content analysis screening experiments
Find out about the effectiveness of CRISPR-Cas9 using pools of Dharmacon™ Edit-R™ synthetic crRNAs in HCA screening experiments.
Application Note
Pooled phenotypic CRISPR screening enables the identification of synergistic drug combinations for cancer therapy
This application note demonstrates how a pooled phenotypic CRISPR screening can be used to identify synergistic drug combinations for cancer therapy
Literature - Publication Review
Linking genes to phenotypes with CRISPR screening
Literature review on the multiple CRIPSR screening techniques available for drug discovery and their benefits.
Whitepaper
Overcoming hurdles in high-throughput profiling of cancer cell responses
Presenting case studies on how functional genomic screening is used to find therapeutic targets, identify patient populations, uncover MoA, investigate drug combinations, and reveal drug resistance and sensitivity
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