IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.
Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.
For research use only. Not for use in diagnostic procedures.
| Feature | Specification |
|---|---|
| Unit Size | 1 Vial (10 doses) |
Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.
Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.
For research use only. Not for use in diagnostic procedures.
IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
Product information
Overview
IVISense Pan Cathepsin 680 is our original “Smart” cathepsin probe; rather than targeting all protease, smart probes become fluorescent only after enzymatic cleavage, which keeps background down and allows detection of activated protease. 24h imaging at 680 nm.
Specifications
| Brand |
IVISense
|
|---|---|
| Fluorescent Agent Type |
Activatable
|
| Imaging Modality |
Fluorescence
|
| Shipping Conditions |
Shipped in Blue Ice
|
| Therapeutic Area |
Arthritis
Atherosclerosis
Inflammation
Oncology/Cancer
|
| Unit Size |
1 Vial (10 doses)
|
| Wave Length |
680 nm
|
Resources
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Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...
This app note highlights using IVISense Pan Cathepsin 680 NIR fluorescent probe for noninvasive in vivo imaging and quantitation...
SDS, COAs, Manuals and more
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言語French国Canada
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言語English国EU
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言語French国France
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言語English国United States
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Lot numberANYLot dateSeptember 6, 2023名前
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