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IVISense Osteo 680 Fluorescent Probe (OsteoSense)

Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISense™ Osteo Fluorescent Imaging probes (OsteoSense™). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.

IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Unit Size 1 Vial (10 doses)

Image and quantify osteoporosis, arthritis, cancer metastases, and other bone diseases, as well as normal bone growth and resorption, in vivo with IVISense™ Osteo Fluorescent Imaging probes (OsteoSense™). As opposed to other imaging modalities such as CT or x-ray which raise the risk of harmful irradiation to the subject, in vivo fluorescence imaging offers no radiation exposure concerns, and when performed with optimized hydroxyapatite-targeted probes such as IVISense Osteo, can image and quantify bone growth and elucidate the biology of bone remodeling.

IVISense Osteo probes are available in 3 wavelengths: 680, 750, and 800.

For research use only. Not for use in diagnostic procedures.

Product Variants
Wave Length: 680 nm
Part #:
NEV10020EX
Wave Length: 750 nm
Part #:
NEV10053EX
Wave Length: 800 nm
Part #:
NEV11105
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Overview

IVISense Osteo NIR fluorescent bisphosphonate imaging probes are designed to bind with high affinity to hydroxyapatite (HA) both in vivo and in vitro. Since HA is known to bind pyrophosphonates and phosphonates as well as synthetic bisphosphonates with high affinity, IVISense Osteo agents offer a safe and easy way to assess the subtle bone mineral changes that occur in bone growth, bone loss, and in diseases that damage bone, using subtherapeutic doses for imaging.

IVISense Osteo 680 is excited by 668 ± 10 mn excitation light and emits at 687 ± 10 mn. Including IVISense Isteo 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped Ambient
Therapeutic Area
Arthritis
Atherosclerosis
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
680 nm

Resources

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Protocol/SOP
Protocol/SOP
SOP: IVISense Osteo 680 (NEV10020EX) for in vivo imaging

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