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IVISense MMP 680 Fluorescent Probe (MMPSense)

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Unit Size 1 Vial (10 doses)

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

For research use only. Not for use in diagnostic procedures.

Product Variants
Wave Length: 645 nm
Part #:
NEV10100
Wave Length: 680 nm
Part #:
NEV10126
Wave Length: 750 nm
Part #:
NEV10168
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Overview

IVISense MMP 680 is excited by 680 + 10 nm excitation light, and emits at 700 + 10 nm. MMP 680 has an optimal imaging window of 24-36 hours after injection, allowing workflow flexibility in acquiring data in large animal cohorts. Including IVISense MMP 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

Specifications

Brand
IVISense
Fluorescent Agent Type
Activatable
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Therapeutic Area
Arthritis
Atherosclerosis
Inflammation
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
680 nm

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Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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Technical data sheet
  • Lot number
    ANY
    Lot date
    September 6, 2023
    名前
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