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IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)

IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Wave Length 680 nm

IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

For research use only. Not for use in diagnostic procedures.

Overview

Folate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.

Folate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped Ambient
Therapeutic Area
Inflammation
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
680 nm

Resources

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Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

Protocol/SOP
Protocol/SOP
SOP: IVISense Folate Receptor 680 (NEV10040) for in vivo imaging
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Whitepaper
Understanding the ‘how’ and ‘why’ of spectral unmixing

In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...

SDS, COAs, Manuals and more

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Safety data sheet
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Technical data sheet
  • Lot number
    ANY
    Lot date
    September 6, 2023
    名前
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