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IVISense Bombesin Receptor 680 Fluorescent Probe (BombesinRSense)

IVISense™ Bombesin Receptor 680 (BombesinRSense™ 680) is a targeted NIR fluorescent probe for in vivo imaging applications that targets bombesin receptors expressed in many types of cancers.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.

Feature Specification
Wave Length 680 nm

IVISense™ Bombesin Receptor 680 (BombesinRSense™ 680) is a targeted NIR fluorescent probe for in vivo imaging applications that targets bombesin receptors expressed in many types of cancers.

For research use only. Not for use in diagnostic procedures.

For research use only. Not for use in diagnostic procedures.

Overview

IVISense Bombesin Receptor 680 fluorescent probe is specific for bombesin receptors (BBRs) expressed in many types of cancer. Bombesin-like peptides and their G-protein coupled receptors have been shown to play a role in cancer and are overexpressed in a variety of tumors, including prostate, breast, lung, CNS, gastric, colon, and renal cell carcinomas.

IVISense Bombesin Receptor 680 imaging agent comprises a 7-amino acid bombesin peptide analog, an NIR fluorophore (ex/em 665/691 nm) and a pharmacokinetic modifier to improve its plasma availability (plasma t1/2 = 30-45 min). This agent can be used to target and quantify upregulation of bombesin receptors (BBR) in vivo associated with tumor proliferation.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped Ambient
Therapeutic Area
Oncology/Cancer
Unit Size
1 Vial (10 doses)
Wave Length
680 nm

Resources

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Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Application Note
Multiplex 2D imaging of NIR molecular imaging agents on the IVIS SpectrumCT platform

Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing...

Protocol/SOP
Protocol/SOP
SOP: IVISense™ Bombesin Receptor 680 (NEV10090) for in vivo imaging
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Whitepaper
Understanding the ‘how’ and ‘why’ of spectral unmixing

In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...

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Safety data sheet
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Technical data sheet
  • Lot number
    ANY
    Lot date
    September 6, 2023
    名前
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