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IVISense 750 MAL Fluorescent Self-Quenching Dye (5 mg) (VivoTag)

Label antibodies, small molecules, proteins, or peptides with IVISense NIR fluorescent dyes.

Revvity’s IVISense™ fluorescent dyes (VivoTag®) for labeling antibodies, small molecules, proteins, or peptides are designed specifically to enable customized development of novel superbright fluorescent imaging agents. Dye properties, such as excellent brightness, hydrolytic stability, and photostability, as well as selection for minimal interaction with biological tissue for no potential loss of specificity, have been optimized and validated for use in in vivo or in vitro imaging.

Available as NHS esters or maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules. Conjugate an optimal 1-3 dyes onto your protein or choose self-quenching dyes to make your own custom fluorogenic probes.

For research use only. Not for use in diagnostic procedures.

Label antibodies, small molecules, proteins, or peptides with IVISense NIR fluorescent dyes.

Revvity’s IVISense™ fluorescent dyes (VivoTag®) for labeling antibodies, small molecules, proteins, or peptides are designed specifically to enable customized development of novel superbright fluorescent imaging agents. Dye properties, such as excellent brightness, hydrolytic stability, and photostability, as well as selection for minimal interaction with biological tissue for no potential loss of specificity, have been optimized and validated for use in in vivo or in vitro imaging.

Available as NHS esters or maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules. Conjugate an optimal 1-3 dyes onto your protein or choose self-quenching dyes to make your own custom fluorogenic probes.

For research use only. Not for use in diagnostic procedures.

Product Variants
Wave Length: 680 nm
Style
NHS
Unit Size
1 Kit
Part #:
NEV11118
Wave Length: 645 nm
Style
NHS
Unit Size
1 mg
Part #:
NEV11173
Wave Length: 645 nm
Style
NHS
Unit Size
5 mg
Part #:
NEV11174
Wave Length: 680 nm
Style
NHS
Unit Size
1 mg
Part #:
NEV11119
Wave Length: 680 nm
Style
NHS
Unit Size
5 mg
Part #:
NEV11120
Wave Length: 800 nm
Style
NHS
Unit Size
1 mg
Part #:
NEV11107
Wave Length: 800 nm
Style
NHS
Unit Size
5 mg
Part #:
NEV11108
Wave Length: 645 nm
Style
MAL
Unit Size
1 mg
Part #:
NEV11273
Wave Length: 645 nm
Style
MAL
Unit Size
5 mg
Part #:
NEV11274
Wave Length: 680 nm
Style
MAL
Unit Size
1 mg
Part #:
NEV11219
Wave Length: 680 nm
Style
MAL
Unit Size
5 mg
Part #:
NEV11220
Wave Length: 680 nm
Style
NHS Self-Quenching
Unit Size
1 mg
Part #:
NEV10121
Wave Length: 680 nm
Style
NHS Self-Quenching
Unit Size
5 mg
Part #:
NEV10122
Wave Length: 750 nm
Style
NHS Self-Quenching
Unit Size
1 mg
Part #:
NEV10123
Wave Length: 750 nm
Style
NHS Self-Quenching
Unit Size
5 mg
Part #:
NEV10124
Wave Length: 750 nm
Style
MAL Self-Quenching
Unit Size
1 mg
Part #:
NEV11223
Wave Length: 750 nm
Style
MAL Self-Quenching
Unit Size
5 mg
Part #:
NEV11224
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Overview

IVISense 750 MAL Fluorescent Self-Quenching Dye is a thiol (-SH, sulfhydryl) reactive, maleimide-containing NIR fluorochrome for labeling small molecules. Its superior brightness makes it particularly well suited for a wide range of both in vivo and in vitro imaging applications using labeled thiol-containing molecules.

It is optimized for single molecule loading, such that labeling a protein with multiple IVISense Self-Quenching Dye molecules will cause a shift in the absorbance of the dye and reduce the signal. Therefore, only choose IVISense Self-Quenching Dyes if your labeling ratio of dye:protein will be 1:1.

Optimized for use with IVIS™ fluorescence imaging systems with expanded wavelength capabilities, IVISense dyes enable quantitative imaging of up to four channels and four different biomarkers of interest in vivo.

Unit size 5 mg

Additional product information

Choose the right IVISense fluorescent dye for your study
Part Number Product Abs/Em (nm)  
IVISense NHS FLOURESCENT LABELING KIT
NEV11118 IVISense 680 NHS 665/688 NHS: Suitable for labeling free amines (typically lysine residues)

Each kit contains IVISense 680 NHS Fluorescent Dye and everything else needed to perform the labeling reaction and purify the labeled product. 
IVISense NHS FLOURESCENT DYES
NEV11173
NEV11174
IVISense 645 NHS 643/660 NHS: Suitable for labeling free amines (typically lysine residues)
NEV11119
NEV11120
IVISense 680 NHS 665/688
NEV11107
NEV11108
IVISense 800 NHS 785/810
IVISense MAL FLUORESCENT DYES
NEV11273
NEV11274
IVISense 645 MAL 643/660 MAL: Suitable for labeling free thiols (typically cysteine residues)
NEV11219
NEV11220
IVISense 680 MAL 665/688
IVISense SELF-QUENCHING DYES
NEV10121
NEV10122
IVISense 680 NHS 673/691 When a protein is labeled with multiple IVISense Self-Quenching Dye molecules, there is a shift in the absorbance of the dye, which will reduce the signal.

Only choose IVISense Self-Quenching Dyes if your labeling ratio of dye:protein will be 1:1. If multiple dyes are to be conjugated onto your protein, a non-self-quenching IVISense Dye should be used. 

NHS and MAL dyes are suitable as noted above.
NEV10123
NEV10124
IVISense 750 NHS 750/775
NEV11223
NEV11224
IVISense 750 MAL 750/776

 

Specifications

Brand
IVISense
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Style
MAL Self-Quenching
Unit Size
5 mg
Wave Length
750 nm

Resources

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Flyer Icon
Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

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eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

Protocol/SOP
Protocol/SOP
PROTOCOL: Antibody and protein near infrared (NIR) labeling with IVISense MAL fluorescent dyes

SDS, COAs, Manuals and more

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Safety data sheet
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Technical data sheet
  • Lot number
    ANY
    Lot date
    September 6, 2023
    名前
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