Skip to main content

IVIS SpectrumCT 2 In Vivo Imaging System

This product replaces the IVIS® SpectrumCT system (part number 128201).

For ultimate ease and flexibility, the IVIS SpectrumCT 2 in vivo optical imaging system integrates 2D & 3D bioluminescence and fluorescence imaging with low-dose CT combining both molecular functional and anatomical in vivo imaging into single system.

For research use only. Not for use in diagnostic procedures.

Product Variant
Unit Size: 1 Unit
Part #:
CLS158737

Overview

The IVIS SpectrumCT 2 in vivo optical imaging system is an integrated platform that combines the full suite of IVIS optical features including; spectral unmixing and 2D and 3D quantitative bioluminescence & fluorescence imaging, with fast, low dose microCT imaging.

Similar to the IVIS Spectrum 2 (part number CLS158738) optical imaging system, the IVIS SpectrumCT 2 incorporates a CCD camera with eXcelon® coating that enables detection of more signal at higher efficiency across a broader spectrum of wavelengths.

The simple user interface along with advanced visualization and analysis tools are driven by our market leading, easy to use Living Image® software. The IVIS SpectrumCT 2 enables longitudinal workflows to characterize disease progression and therapeutic effect throughout the complete experimental time frame with both quantitative CT and optical reconstructions. Fast imaging and the ability to image multiple animals offers the throughput required to scan large cohorts of animals quickly and draw sound conclusions from your experimental data.

Additional product information

Features and benefits

High Sensitivity

High sensitivity

Exclusivity to patented CCD camera with eXcelon coating for high sensitivity imaging

Combined modalities

Combined modalities

Integrating optical imaging with microCT for simultaneous functional and anatomical studies in a single system

High Throughput

High throughput

Standard 5 mice configuration or up to 10 mice capacity using optional manifold

Rapid Imaging

Rapid imaging

Fast data acquisition allows quick visualization of images in real-time

Trans-illumination

Trans-illumination

Imaging below the specimen for sensitive detection and quantification of deep fluorescent sources

Epi-illumination

Epi-illumination

Imaging above the specimen ideal for high throughput workflow

Spectral Unmixing

Spectral unmixing

Remove autofluorescence & easily identify, separate, and quantify multiplexed fluorescent signals

Analysis Software

Analysis software

Broadly adopted, easy to use, and intuitive, Living Image visualization and analysis software


Complimentary Living Image™ software licenses are provided with the IVIS systems and upon request.

 

High-performance CCD camera

The camera and coating facilitate detection of more signal at higher efficiency across a broader spectrum of wavelengths throughout the visible and NIR spectrum - giving you:

  • Improved signal-to-noise ratio for both bioluminescent and fluorescent signals
  • Increased bandwidth to encompass a wider range of NIR fluorescent probes

Camera highlights

  • Patented eXcelon® coating
  • Back-illuminated, thermoelectrically cooled (-90°C) CCD
  • High quantum efficiency (peak >95%)
  • 2048 x 2048 imaging pixels with 13.5 micron pixel size
  • Low read noise
signal to noise

 

qe camera with excelon

 

 

Fast, low-dose microCT

Automated optical and high-performance, low-dose microCT integration enabled through:

  • Constant horizontal gantry motion and the flat panel detector
  • Stable revolving animal platform table that rotates 360° to acquire full 3D data
  • Maintaining an average dose per scan at 13mGy, ideal for longitudinal studies
  • Simultaneous scanning of up to 2 mice
  • Fast scanning and reconstruction times of less than a minute
ivis spectrumct2 detector xray rotating stage

 

Bring your in vivo images to life with Living Image software

Broadly adopted imaging software that sets the industry standard for ease of use and flexibility

  • Comprehensive set of tools for 2D and 3D data analysis
  • One click 3D reconstructions
  • Spectral unmixing algorithms to easily obtain and separate simultaneous fluorescent readouts or remove unwanted autofluorescence
  • Co-register optical imaging with other modalities (e.g., CT, MRI, SPECT, PET)
  • Auto settings for easy image acquisition
  • Batch processing analysis tools
  • Generation of animated movies and publication ready figures
  • Flexible remote review for convenient offline analysis of data sets
  • Included in IVIS purchase
computer with living image

 

Which IVIS system is best for your research?
  IVIS spectrum 2 IVIS spectrumCT 2 IVIS lumina S5 IVIS lumina X5 IVIS lumina III IVIS lumina LT IVIS lumina XRMS
Capacity Up to 10 mice* Up to 10 mice* Up to 10 mice* Up to 10 mice* Up to 5 mice** Up to 5 mice** Up to 3 mice
Benchtop format    
2D Bioluminescence / Fluorescence ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔
3D Bioluminescence / Fluorescence ✔/✔ ✔/✔          
Enhanced Fluorescence capabilities  
Integrated standard x-ray            
Integrated high resolution x-ray            
Integrated CT            
Optical FOV (cm) (Nominal) 4-22.5 4-22.5 10-22.5 10-22.5 5-12(2.6**) 5-12(2.6**) 5-12
Wavelength range (nm) 415-850 415-850 410-865 410-865 410-865 415-875 410-865
For additional comparison information please refer to the IVIS Comparison flyer under the ‘Resources’ tab
*Using optional manifold kit
**Using expansion lens

 

Specifications

Height
206.0 cm
Width
65.0 cm
Brand
IVIS
Imaging Modality
microCT Imaging
Optical Imaging
Unit Size
1 Unit

Video gallery

Resources

Are you looking for resources, click on the resource type to explore further.

1-2 of 2 Resources
Whitepaper Icon
Whitepaper
The role of in vivo imaging in drug discovery and development

The primary goal of preclinical imaging is to improve the odds of clinical success and reduce drug discovery and development time...

Whitepaper Icon
Whitepaper
Understanding the ‘how’ and ‘why’ of spectral unmixing

In vivo fluorescence imaging displays a very broad utility and has become a well-established modality for functional imaging in...

Scroll Icon