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IVIS Spectrum 2 In Vivo Imaging System

This product replaces the IVIS Spectrum system (part number 124262).

As the leader in optical imaging with thousands of publications using our flagship IVIS® Spectrum platform, the IVIS Spectrum 2 system is the next generation in optical imaging. Designed with an innovative camera with patented coating that delivers high sensitivity 2D and 3D bioluminescence and fluorescence imaging capabilities - the IVIS Spectrum 2 gives you the flexibility you need for your in vivo imaging studies.

For research use only. Not for use in diagnostic procedures.

Overview

Building upon the IVIS Spectrum in vivo optical system with proven 2D bioluminescence and 2D fluorescence imaging and 3D optical tomography capabilities combined in a single system, the IVIS Spectrum 2 is our next generation in optical imaging. This advanced imaging system incorporates a CCD camera with eXcelon® coating that enables detection of more signal at higher efficiency across a broader spectrum of wavelengths. With exclusivity to this innovative camera for in vivo imaging, the IVIS Spectrum 2 preclinical optical imaging system delivers the sensitivity you demand for non-invasive longitudinal imaging to better understand early disease-related biological changes, track disease progression, and help guide the drug development process.

Additional product information

Features and benefits

High Sensitivity

High sensitivity

Exclusivity to patented CCD camera with eXcelon coating for high sensitivity imaging

Rapid Imaging

Rapid imaging

Fast data acquisition allows quick visualization of images in real-time

High Throughput

High throughput

Standard 5 mice configuration or up to 10 mice capacity using optional manifold

Trans-illumination

Trans-illumination

Imaging below the specimen for sensitive detection and quantification of deep fluorescent sources

Epi-illumination

Epi-illumination

Imaging above the specimen ideal for high throughput workflow

Co-registration

Co-registration

Seamless co-registration of optical data with other modalities, e.g., CT, MRI, SPECT, PET, Ultrasound

Spectral Unmixing

Spectral unmixing

Remove autofluorescence & easily identify, separate, and quantify multiplexed fluorescent signals

Analysis Software

Analysis software

Broadly adopted, easy to use, and intuitive, Living Image® visualization and analysis software


Complimentary Living Image™ software licenses are provided with the IVIS systems and upon request.

 

High-performance CCD camera

The camera and coating facilitate detection of more signal at higher efficiency across a broader spectrum of wavelengths throughout the visible and NIR spectrum - giving you:

  • Improved signal-to-noise ratio for both bioluminescent and fluorescent signals
  • Increased bandwidth to encompass a wider range of NIR fluorescent probes

Camera highlights

  • Patented eXcelon® coating
  • Back-illuminated, thermoelectrically cooled (-90°C) CCD
  • High quantum efficiency (peak >95%)
  • 2048 x 2048 imaging pixels with 13.5 micron pixel size
  • Low read noise
signal to noise

 

qe camera with excelon

 

Bring your in vivo images to life with Living Image software

Broadly adopted imaging software that sets the industry standard for ease of use and flexibility

  • Comprehensive set of tools for 2D and 3D data analysis
  • One click 3D reconstructions
  • Spectral unmixing algorithms to easily obtain and separate simultaneous fluorescent readouts or remove unwanted autofluorescence
  • Co-register optical imaging with other modalities (e.g., CT, MRI, SPECT, PET)
  • Auto settings for easy image acquisition
  • Batch processing analysis tools
  • Generation of animated movies and publication ready figures
  • Flexible remote review for convenient offline analysis of data sets
  • Included in IVIS purchase
computer with living image

 

Which IVIS system is best for your research?
  IVIS spectrum 2 IVIS spectrumCT 2 IVIS lumina S5 IVIS lumina X5 IVIS lumina III IVIS lumina LT IVIS lumina XRMS
Capacity Up to 10 mice* Up to 10 mice* Up to 10 mice* Up to 10 mice* Up to 5 mice** Up to 5 mice** Up to mice
Benchtop format    
2D Bioluminescence / Fluorescence ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔ ✔/✔
3D Bioluminescence / Fluorescence ✔/✔ ✔/✔          
Enhanced Fluorescence capabilities  
Integrated standard x-ray            
Integrated high resolution x-ray            
Integrated CT            
Optical FOV (cm) (Nominal) 4-22.5 4-22.5 10-22.5 10-22.5 5-12(2.6**) 5-12(2.6**) 5-12
Wavelength range (nm) 415-850 415-850 410-865 410-865 410-865 415-875 410-865
For additional comparison information please refer to the IVIS Comparison flyer under the ‘Resources’ tab
*Using optional manifold kit
**Using expansion lens

 

Specifications

Dimensions 65.0 cm (W) x 206.0 cm (H)
Brand
IVIS
Imaging Modality
2D and 3D Bioluminescence
2D and 3D Fluorescence
Unit Size
1 Unit

Video gallery

Resources

Are you looking for resources, click on the resource type to explore further.

1-6 of 22 Resources
Technical Brief Icon
Technical Brief
3D optical and microCT data – The power of multimodality imaging

3D optical and microCT data – The power of multimodality imaging

Case Study Icon
Case Study
A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity

CAR-T therapy has achieved tremendous success in treating blood malignancies, however treating solid tumors with this therapy has...

Publication Icon
Literature - Publication Review
Applications of In Vivo bioluminescence imaging for SARS-CoV-2

Scientists continue to explore several options to treat SARS-CoV-2 infection with hundreds of therapeutics at various phases of...

Publication Icon
Literature - Publication Review
Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors

Adoptive cell transfer using chimeric antigen receptor (CAR-T) cell therapy in which the patient’s T-cells are extracted...

Brochure Icon
Brochure
Comprehensive drug discovery workflows brochure

The next breakthrough therapy could begin here. Our comprehensive drug discovery solutions cover every stage, from target...

Publication Icon
Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model

A large percentage of Type 2 diabetes mortality is related to cardiovascular complications. Consequently, there is a critical need...

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