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GSP Neonatal 17α-OH-progesterone kit
GSP Neonatal 17α-OH-progesterone kit
Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11α-hydroxylase deficiency.
Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.
| Feature | Specification |
|---|---|
| Application | Newborn Screening |
Congenital adrenal hyperplasia (CAH) is a genetic disorder and the most severe form of the disease can lead to a life threatening condition during the first weeks of life. The disease is caused by enzyme defects in steroid biosynthesis, the most frequent types being 21- and 11α-hydroxylase deficiency.
Products may not be licensed in accordance with the laws in all countries. Please check with your local representative for availability.
GSP Neonatal 17α-OH-progesterone kit
GSP Neonatal 17α-OH-progesterone kit
Product information
Overview
These types represent 95% of CAH cases and in both, the 17α-OH progesterone (17OHP), a precursor of cortisol, is increased. The determination of 17OHP is thus a useful screening method for 95% of all CAH cases.
GSP Neonatal 17α-OH-progesterone assay
The GSP Neonatal 17α-OH-progesterone assay is intended for the quantitative determination of 17OHP in dried blood spot specimens as an aid in screening newborns for CAH.
- Incubation time 3 h
- Sensitive, robust DELFIA chemistry for confidence in results
- Not affected by EDTA, citrate or heparin in samples
- All reagents are ready to use
- Contains reagents and plates for 1152 tests (12 plates)
Specifications
| Application |
Newborn Screening
|
|---|---|
| Brand |
GSP®
|
| Detection Modality |
Time-Resolved Fluorescence (TRF)
|
| Disorders |
Congenital Adrenal Hyperplasia (CAH)
|
| Instrument Compatibility |
GSP
|
| Quantity |
1152 tests
|
| Sample Type |
Dried blood spots
|
| Technology |
DELFIA
|
| Unit Size |
12 plates
|
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