125I Radioiodination Services

From your initial inquiry, through scientific consultation, radioiodination, purification, packaging and shipment, you can trust the attentiveness of our custom radioiodination team to diligently manage the ¹²⁵I radiolabeling of your proprietary molecule.

From the start, you will have direct access to our years of experience in custom iodination. Our collaborative team will confidentially advise you on the appropriate 125I labeling technique that best maintains the functional structure, biological activity and radiochemical stability of your unique molecule. Retaining the molecule's integrity is essential for the success of radiometric assays such as:

• Pharmacokinetic/Pharmacodynamic (PK/PD)
• Receptor Ligand Binding
• Quantitative Whole Body Autoradiography (QWBA)
• Radioimmunoassay (RIA)

Once your precious molecule is in our hands, expect a high yield and quick turnaround. To keep you on pace, your molecule will be efficiently iodinated, purified and packaged with the appropriate buffer then shipped back to you in a secure container within a week. Trust Revvity's proficiency in logistics and management of radiolabeling services.

Available radioiodination (¹²⁵I) labeling services include:

• Bolton-Hunter Reagent – for ¹²⁵I labeling peptides or proteins containing lysine residues
• Chloramine-T – for iodination labeling peptides and proteins naturally containing, or chemically modified to introduce either tyrosine or histidine
• Iodogen - for custom radioiodination labeling peptides or proteins containing tyrosine or histidine side chain rings
• Lactoperoxidase – for custom ¹²⁵I labeling peptides and proteins naturally containing or chemically modified to contain tyrosine
• Other custom labeling methods – we will review proposals for custom iodination specific to your unique compound