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Case Study

Unlocking excellence in high-throughput nucleic acid extraction

Meeting the Demands of Modern Molecular Biology

The landscape of molecular testing has undergone a dramatic transformation. As genomic research, personalized medicine, and infectious disease surveillance advance at unprecedented rates, laboratories worldwide face mounting pressure to process more samples with greater efficiency and precision than ever before.

This evolution isn't merely about increased volume—it represents a fundamental shift in how we approach molecular biology. Today's researchers and clinicians require extraction methods that deliver consistently high-quality nucleic acids across diverse sample types, while maintaining workflow efficiency and data integrity.

The case studies that demonstrates how three distinct organizations—a pioneering biobank, a transplantation immunology center, and a national blood safety program—have transformed their operations through strategic automation of their nucleic acid extraction workflows.

CEPH biobank: powering large-scale genomic research

  • Processed over 61,000 challenging saliva samples with consistent DNA yields of 62-77 μg
  • Achieved exceptional genomic quality numbers (6.1-6.6 GQN)
  • Supported 96 % + genotyping success rates for critical epidemiological studies

German red cross: advancing transplantation medicine

  • Processes 4,000-5,000 samples monthly with minimal dropout rates
  • Supports high-resolution HLA typing for stem cell and organ transplantation
  • Maintains > 97% success rate across 40,000+ annual samples

Bio-manguinhos: safeguarding blood supply

  • Enables testing of 3.5 million blood donations annually
  • Reduces donor deferral periods from one year to one month
  • Enhances detection of low-abundance pathogens with 1 mL sample capacity

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Unlocking excellence in high-throughput nucleic acid extraction