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Application Note

SARS-CoV-2 detection in saliva using bead-beating homogenization and an RT-PCR kit

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In infectious disease research, the use of saliva sampling as a less invasive and more comfortable method of detection is attractive to many labs. In this application note, the Omni Bead Ruptor Elite bead mill homogenizer is highlighted for its effectiveness in homogenizing saliva samples for PCR-based SARS-CoV-2 detection. This study found 100% agreement in detecting SARS-CoV-2 from saliva in samples with recently confirmed infections, as detected by standard nasopharyngeal swab PCR methods. The homogenization step is a crucial consideration within this workflow process.

For research use only. Not for use in diagnostic procedures.

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SARS-CoV-2 detection in saliva using bead-beating homogenization and an RT-PCR kit